A meta-analysis of 117 experiments evaluated the effects of cognitive load on duration judgments. Cognitive load refers to information-processing (attentional or working-memory) demands. Six types of cognitive load were analyzed to resolve ongoing controversies and to test current duration judgment theories. Duration judgments depend on whether or not participants are informed in advance that they are needed: prospective paradigm (informed) versus retrospective paradigm (not informed). With higher cognitive load, the prospective duration judgment ratio (subjective duration to objective duration) decreases but the retrospective ratio increases. Thus, the duration judgment ratio differs depending on the paradigm and the specific type of cognitive load. As assessed by the coefficient of variation, relative variability of prospective, but not retrospective, judgments increases with cognitive load. The prospective findings support models emphasizing attentional resources, especially executive control. The retrospective findings support models emphasizing memory changes. Alternative theories do not fit with the meta-analytic findings and are rejected.
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http://dx.doi.org/10.1016/j.actpsy.2010.03.006 | DOI Listing |
Sci Rep
January 2025
Department of Experimental Medicine, University of Campania "Luigi Vanvitelli", Via Santa Maria Di Costantinopoli 16, 80138, Naples, Italy.
Patients with Mild Cognitive Impairment (MCI) may exhibit poorer performance in visuomotor tasks than healthy individuals, particularly under conditions with high cognitive load. Few studies have examined reaching movements in MCI and did so without assessing susceptibility to distractor interference. This proof-of-concept study analyzed the kinematics of visually guided reaching movements towards a target dot placed along the participants' midsagittal/reaching axis.
View Article and Find Full Text PDFTraffic Inj Prev
January 2025
School of Intelligent Transportation and Engineering, Guangzhou Maritime University, Guangzhou, China.
Objective: The objective of this study was to assess drivers' visual search patterns and cognitive load during driving in curved tunnels. Specifically, we aimed to investigate how different curved tunnel geometries (tunnel radii, turning directions) and zones (entrance, middle, exit) influence drivers' saccadic eye movements. This understanding can inform the development of safer tunnel designs and driving guidelines.
View Article and Find Full Text PDFInt J Occup Saf Ergon
January 2025
UR 3450 DevAH, Université de Lorraine, France.
. Musculoskeletal disorders (MSDs) represent a prevalent global occupational health concern, primarily associated with high biomechanical solicitations, mental workload and work pace. Although cobots have shown promise in reducing risks of MSDs, a question of interest still persists as to how the pace in hybrid human-machine collaboration will affect the operator, in terms of both physical and cognitive health and the production.
View Article and Find Full Text PDFJ Alzheimers Dis
January 2025
Department of Neurology, Indiana University School of Medicine, Indianapolis, IN, USA.
Background: Although previous studies have shown that cognitive decline in Alzheimer's disease (AD) is associated with various risk factors, they primarily focused on late-onset AD (LOAD).
Objective: We aim to evaluate the differential impact of risk factors on the cognitive decline between early-onset AD (EOAD, onset < 65 years) and LOAD (onset 65 years) and explore the longitudinal effect of Apolipoprotein E allele 4 ( ε4) on cortical atrophy in both cohorts.
Methods: Using data from 212 EOAD and 1101 LOAD participants in the Alzheimer's Disease Neuroimaging Initiative (ADNI), we conducted multivariable mixed-effect models to evaluate the impact of ε4, education, hypertension, diabetes, dyslipidemia, and body mass index on cognitive performance.
J Prev Alzheimers Dis
January 2025
CenExel iResearch, Atlanta, GA, USA.
Background: Soluble species of multimeric amyloid-beta including globular amyloid-beta oligomers (AβOs) and linear amyloid-beta protofibrils are toxic to neurons. Sabirnetug (ACU193) is a humanized monoclonal antibody, raised against globular species of soluble AβO, that has over 650-fold greater binding affinity for AβOs over monomers and appears to have relatively little binding to amyloid plaque.
Objectives: To assess safety, pharmacokinetics, and exploratory measures including target engagement, biomarker effects, and clinical efficacy of sabirnetug in participants with early symptomatic Alzheimer's disease (AD; defined as mild cognitive impairment and mild dementia due to AD).
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