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Healthcare outcomes and special education eligibility in children with congenital CMV.
PLoS One
December 2024
Department of Pediatrics, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas, United States of America.
Objectives: Congenital cytomegalovirus disease (cCMV) can have significant sensory and neurodevelopmental sequelae throughout childhood. Many of these sequalae are consistent with special education eligibility, but the special education needs of affected children have not been systematically studied.
Methods: Retrospective chart reviews from two cohorts of cCMV children receiving care in a large tertiary care children's hospital were included in this study: a historical research cohort (N = 186, 41% symptomatic at birth) and a contemporary clinical cohort of cCMV patients (N = 112, 68% symptomatic at birth).
Early Detection of Basal Cell Carcinoma of Skin From Medical History.
Qual Manag Health Care
December 2024
Author's Affiliation: Health Services Research, Department of Health Administration and Policy, College of Public Health, George Mason University, Fairfax, Virginia.
Background And Objectives: Basal cell carcinoma (BCC) is the most common form of skin cancer, originating from basal cells in the skin's outer layer. It frequently arises from prolonged exposure to ultraviolet (UV) radiation from the sun or tanning beds. Although BCC rarely metastasizes, it can cause significant local tissue damage if left untreated.
View Article and Find Full Text PDFKSDKG: construction and application of knowledge graph for kidney stone disease based on biomedical literature and public databases.
Health Inf Sci Syst
December 2024
Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, 510080 China.
Article Synopsis
- Kidney stone disease (KSD) is a growing urological issue, and this paper aims to create a knowledge graph to improve the access and understanding of KSD-related information for medical professionals.
- Text from PubMed was analyzed and integrated with various public databases to build a large-scale Kidney Stone Disease Knowledge Graph (KSDKG), which includes over 90 million data points derived from nearly 30,000 articles.
- The developed KSDKG demonstrates its utility through case studies, revealing new clinical insights and enabling better understanding of the connections between microbes, drugs, and diseases related to KSD, ultimately contributing significantly to medical research.
Ontology of clinical practice guidelines for Integrated Traditional Chinese and Western Medicine.
J Evid Based Med
September 2024
Center for Evidence-Based and Translational Medicine, Zhongnan Hospital of Wuhan University, Wuhan, China.
Objective: Clinical practice guidelines (CPGs) for Integrated Traditional Chinese and Western Medicine (TCM and WM) are important medical documents used to assist medical decision-making and are of great significance for standardizing clinical pathways. However, due to the constraints of text format, it is difficult for Integrated TCM and WM CPGs to play a real role in medical practice. In addition, how to standardize the structure and semantic relationships between Integrated TCM and WM CPG knowledge, and realize the construction of computable, sharable and reliable CPGs, remains an urgent issue to be addressed.
View Article and Find Full Text PDFBotulinum Toxin Type A (BoNT-A) Use for Post-Stroke Spasticity: A Multicenter Study Using Natural Language Processing and Machine Learning.
Toxins (Basel)
August 2024
Department of Physical Medicine and Rehabilitation, Rio Hortega University Hospital, 47007 Valladolid, Spain.
We conducted a multicenter and retrospective study to describe the use of botulinum toxin type A (BoNT-A) to treat post-stroke spasticity (PSS). Data were extracted from free-text in electronic health records (EHRs) in five Spanish hospitals. We included adults diagnosed with PSS between January 2015 and December 2019, stratified into BoNT-A-treated and untreated groups.
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