We report that the N terminus of the type III secretion system translocator proteins EspB, EspD, and EspA mediate protein secretion and translocation from wild-type enteropathogenic Escherichia coli and hypersecretion from sepL and sepD mutants. EspA containing the translocation signal of Map and Tir containing the secretion signal of EspA are biologically active.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2897685PMC
http://dx.doi.org/10.1128/JB.00046-10DOI Listing

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