Bacillus anthracis is a Gram-positive, spore-forming bacterium representing the etiological agent of acute infectious disease anthrax, a lethal but rare disease of animals and humans in nature. With recent use of anthrax as a bioweapon, a number of techniques have been recently developed and evaluated to facilitate its rapid detection of B. anthracis in the environment as well as in point-of-care settings for humans suspected of exposure to the pathogen. Complex laboratory methods for B. anthracis identification are required since B. anthracis has similarities with other Bacillus species and its existence in both spore and vegetative forms. This review discusses current challenges and various improvements associated with anthrax agent detection.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.mimet.2010.04.005 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
The anthrax pathogen can remain dormant as spores in soil for many years. This applies to both natural foci and to sites of anthropogenic activity such as tanneries, abattoirs, or wool factories. The A.
View Article and Find Full Text PDFIdentification of Strains from Animal Cases in Ethiopia and Genetic Characterization by Whole-Genome Sequencing.
Pathogens
January 2025
Aklilu Lemma Institute of Pathobiology, Addis Ababa University, Addis Ababa P.O. Box 1176, Ethiopia.
Anthrax is a zoonotic disease characterized by rapid onset with usual fatal outcomes in livestock and wildlife. In Ethiopia, anthrax is a persistent disease; however, there are limited data on the isolation and molecular characterization of strains. This study aimed to characterize isolated from animal anthrax outbreaks between 2019 and 2024, from different localities in Ethiopia.
View Article and Find Full Text PDFNegative Association of Gulf War Illness Symptomatology with Predicted Binding Affinity of Anthrax Vaccine Antigen to Human Leukocyte (HLA) Class II Molecules.
Vaccines (Basel)
January 2025
The GWI and HLA Research Groups, Brain Sciences Center, Department of Veterans Affairs Health Care System, Minneapolis, MN 55417, USA.
Background: Anthrax is a serious disease caused by () with a very high mortality when the spores of are inhaled (inhalational anthrax). Aerosolized spores can be used as a deadly bioweapon. Vaccination against anthrax is the only effective preventive measure and, hence, the anthrax vaccine was administered to United States (and other) troops during the 1990-91 Gulf War.
View Article and Find Full Text PDFElectrochemical immunosensor for PA toxin using a polypyrrole-gold nanoparticle/multiwall carbon nanotube sensing platform and cadmium sulphide nanocrystal signal tag.
Anal Methods
January 2025
Defence Research and Development Establishment, Jhansi Road, Gwalior, Madhya Pradesh 474002, India.
A sandwich electrochemical immunosensor was proposed for the sensitive detection of protective antigen ( PA) toxin based on cadmium sulphide nanocrystals (CdS NCs) and polypyrrole-gold nanoparticle-modified multiwalled carbon nanotubes (PPy-AuNPs/MWCNTs). Herein, PPy-AuNPs/MWCNTs were used as a biocompatible and conducting matrix for immobilization of rabbit anti-PA antibody [RαPA antibody, capturing antibody (Ab1)] and to facilitate excellent electrical conductivity. PPy-AuNPs/MWCNTs were synthesized through a one-step chemical reaction of pyrrole and Au on the surface of MWCNTs.
View Article and Find Full Text PDFMitigating negative impacts of drought on oak seedlings performances through plant growth-promoting rhizobacteria.
J Environ Manage
January 2025
INRAE, Aix-Marseille Univ., UMR RECOVER, Aix-en-Provence, France.
Drought stress during the plant's growing season is a serious constraint to plant establishment in arid and semiarid Mediterranean ecosystems. Plant growth promoting rhizobacteria (PGPR) as environmentally friendly and innovative management approach can be used to produce seedlings better adapted to these environments. We tested native PGPR strains isolated from drought-tolerant tree and shrub species originating from two climatically contrasting regions: hot-dry (Dehloran) and milder Mediterranean climate (Ilam).
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!