An estimated 25% of the British population suffers from some form of allergic condition. Atopic dermatitis and food sensitivities are more common in infants and younger children, with hay fever (seasonal allergic rhinitis), perennial allergic rhinitis and allergic asthma developing throughout adolescence. Allergic reactions occur as a result of an interaction between allergen and mast cells via the antibody immunoglobulin E (IgE). Classic symptoms include itching, redness and swelling. These symptoms, and their time course, help the health professional to differentiate between allergic and non-allergic symptoms. Avoidance plays a part in management. Anaphylaxis is a medical emergency and recent guidelines recommend early use of epinephrine in patient with a severe allergic-type reaction.
Download full-text PDF |
Source |
---|
Front Allergy
January 2025
Department of Biomedical Science and Technology, School of Biological Sciences, Ramakrishna Mission Vivekananda Educational and Research Institute (RKMVERI), Kolkata, India.
Increasing evidence demonstrates a robust link between environmental pollutants and allergic reactions, with air and indoor pollution exacerbating respiratory allergies and climate change intensifying seasonal allergies. Comprehensive action, including government regulations, public awareness, and individual efforts, is essential to mitigate pollution's impact on allergies and safeguard public health and ecological balance. Recent findings indicate a strong correlation between environmental pollutants and allergic reactions, with air pollution from vehicular emissions and industrial activities exacerbating respiratory allergies like asthma and allergic rhinitis.
View Article and Find Full Text PDFFront Immunol
January 2025
Central Research Laboratory, The First Affiliated Hospital of Soochow University, Suzhou, China.
Background: Uncontrolled severe eosinophilic chronic rhinosinusitis (eCRS) is associated with elevated levels of Th2 cells and raised immunoglobulin concentrations in nasal polyp tissue. eCRS is characterized by high eosinophilic infiltration and type 2 inflammation. Gαi1/3 proteins participate in allergic inflammation by regulating immune cells.
View Article and Find Full Text PDFSci Rep
January 2025
Department of Physiology and Immunology, Faculty of Medicine, University of Prishtina "Hasan Prishtina", Bulevardi I Deshmoreve P.N., Prishtina, Kosovo.
Allergic rhinitis and asthma are common respiratory conditions with complex etiologies involving genetic, environmental, and physiological factors. In these conditions, the role of thyroid function remains underexplored. This study enrolled 116 participants with a mean age of 29.
View Article and Find Full Text PDFOral Oncol
January 2025
Department of Otolaryngology, The Affiliated Traditional Chinese Medicine Hospital, Southwest Medical University, Luzhou 646000 Sichuan, China. Electronic address:
Tissue Cell
December 2024
Department of Facial Features, 970 Hospital, Joint Service Support Force of the Chinese People's Liberation Army, Yantai, Shandong, China. Electronic address:
Allergic rhinitis (AR), common in children and adolescents, involves Lysophosphatidylcholine acyltransferase 1 (LPCAT1) catalyzing surfactant lipid biosynthesis and suppressing endoplasmic reticulum expression. However, the precise mechanism underlying the impact of LPCAT1 on epithelial cell damage in AR remains elusive. Hence, the present investigation elucidated the potential effect of LPCAT1 on epithelial cell damage in AR by inhibiting endoplasmic reticulum stress.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!