Now single spines: monitoring neuronal membrane potential with submicron and submillisecond resolution.

J Physiol

Department of Physiology and Biophysics, Georgetown University Medical Center, 3970 Reservoir Road, N.W. Washington, DC 20007, USA.

Published: April 2010

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2872725PMC
http://dx.doi.org/10.1113/jphysiol.2010.189589DOI Listing

Publication Analysis

Top Keywords

single spines
4
spines monitoring
4
monitoring neuronal
4
neuronal membrane
4
membrane potential
4
potential submicron
4
submicron submillisecond
4
submillisecond resolution
4
single
1
monitoring
1

Similar Publications

Background: Significant osseous defects or osteonecrosis, precipitated by open fractures, infections, or neoplastic conditions, represent infrequent yet critical medical conditions. The free vascularized fibular graft (FVFG) is a challenging but straightforward, reliable surgical intervention for the reconstruction of defects across various anatomical regions. This study aims to compare, quantify, and demonstrate the FVFG's versatility.

View Article and Find Full Text PDF

Cannabinoid receptor 1 (CB1) regulates synaptic transmission through presynaptic receptors in nerve terminals, and its physiological roles are of clinical relevance. The cellular sources and synaptic targets of CB1-expressing terminals in the human cerebral cortex are undefined. We demonstrate a variable laminar pattern of CB1-immunoreactive axons and electron microscopically show that CB1-positive GABAergic terminals make type-2 synapses innervating dendritic shafts (69%), dendritic spines (20%) and somata (11%) in neocortical layers 2-3.

View Article and Find Full Text PDF

Background: Blinding is essential for mitigating biases in trials of low back pain (LBP). Our main objectives were to assess the feasibility of blinding: (1) participants randomly allocated to active or placebo spinal manual therapy (SMT), and (2) outcome assessors. We also explored blinding by levels of SMT lifetime experience and recent LBP, and factors contributing to beliefs about the assigned intervention.

View Article and Find Full Text PDF

Non-traumatic lumbar spondylolysis with contralateral pedicle and lamina fracture: a case report and review of the literature.

BMC Musculoskelet Disord

January 2025

Spine Center, Department of Orthopedics, Shanghai Changzheng Hospital, Second Affiliated Hospital of Naval Medical University, No.415 Feng Yang Road, Shanghai, 200003, China.

Lumbar spondylolysis of a single lumbar vertebra with a fracture of the pedicle on the opposite side, as well as fractures of both pedicles and bilateral spondylolysis, have been extensively reported in the literature. These cases are commonly linked to factors such as trauma, sports activities, and spinal surgeries. We report a unique case of a unilateral lumbar spondylolysis with a fracture on the opposite side including the pedicle and lamina.

View Article and Find Full Text PDF

Objective: This study aimed to compare the use of the endoscopic drill (ED) with the extra-endoscopic trephine (EET) in treating lumbar disc herniations with regard to efficiency, safety, and clinical outcomes.

Methods: From January 2022 and June 2023, 136 patients who had the single-level LDH and received the transforaminal endoscopic surgery were divided into two groups according to the foraminoplasty technique: the EET group (n = 69) and the ED group (n = 67). Surgery-related parameters, complications, Visual Analogue Scale (VAS, 0-10), and Oswestry Disability Index (ODI, 0-100%) were assessed and compared among two groups.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!