The success of knee treatment programs and surgery must be assessed, in part, by both the ability to return patients to work and the documentation of any work-related limitations. Existing occupational rating scales do not rate, in a valid manner, the effect of altered knee function on work activities. We performed a prospective randomized clinical trial in which two different occupational rating systems were tested on 50 patients. One system used job titles and an arbitrary numeric scale for rating occupations; the other used specific criteria for rating job functions according to the intensity, frequency, and duration of certain tasks. The results showed that an effective and valid rating format should consist of five specific objectives: 1) evaluation of different knee functions that typically occur in the work environment; 2) evaluation of work activities separately from sports activities; 3) detection of patients who may have remained at an occupation but who have significantly modified work activities because of knee symptoms; 4) identification of patients who continue to work despite experiencing moderate to severe symptoms; and 5) identification of patients whose work activities decrease because of nonknee-related factors. Furthermore, the results showed that an effective rating system should identify common data reduction errors that can bias the results in analyzing knee-related occupational limitations. The rating system developed circumvents the bias introduced by these anomalies. This system, if adopted by other researchers, would allow for the comparison of treatment results among studies.
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http://dx.doi.org/10.1177/036354659101900214 | DOI Listing |
Eur J Neurosci
March 2025
Parkinson's Disease and Movement Disorders Clinic, Bangalore, India.
The release of synaptic vesicles (SVs) at the synaptic junction is a complex process involving various specialized proteins that work in unison. Among these, Bassoon has emerged as a significant protein, particularly noted for its association with various neurological and aging-related diseases. Due to its structural and functional roles, Bassoon has become a focus of recent research, especially in understanding its implications in neurodegenerative and psychiatric disorders.
View Article and Find Full Text PDFACS Appl Mater Interfaces
March 2025
State Key Laboratory of Luminescent Materials and Devices, Institute of Polymer Optoelectronic Materials and Devices, Guangdong Provincial Key Laboratory of Luminescence from Molecular Aggregates, South China University of Technology, Guangzhou 510640, P. R. China.
The relationship between the structure and function of condensed matter is complex and changeable, which is especially suitable for combination with machine learning to quickly obtain optimized experimental conditions. However, little research has been done on the effect of temperature on condensed matter and how it affects device performance because the difference between the in situ physical property parameters (which are lowered by the surface tension and mixing entropy) and the basic parameters of the bulk makes accurate AI predictions difficult. In this work, P3HT/ITIC was chosen as the donor/acceptor material for the active layer of organic phototransistors (OPTs).
View Article and Find Full Text PDFJ Prev Alzheimers Dis
March 2025
Department of Pathophysiology School of Basic Medicine Key Laboratory of Education Ministry/Hubei Province of China for Neurological Disorders Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. Electronic address:
Background: The swift rise in the prevalence of Alzheimer's disease (AD) alongside its significant societal and economic impact has created a pressing demand for effective interventions and treatments. However, there are no available treatments that can modify the progression of the disease.
Methods: Eight AD brain tissues datasets and three blood datasets were obtained.
Atherosclerosis
March 2025
University Medical Center Mainz, Department of Cardiology at the Johannes Gutenberg University, Germany; German Cardiovascular Research Center (DZHK), Partner Site Rhine Main, Mainz, Germany.
Soil and water pollution represent significant threats to global health, ecosystems, and biodiversity. Healthy soils underpin terrestrial ecosystems, supporting food production, biodiversity, water retention, and carbon sequestration. However, soil degradation jeopardizes the health of 3.
View Article and Find Full Text PDFVaccine
March 2025
Robert Koch Institute, Am Nordufer 20, 13353 Berlin, Germany. Electronic address:
Introduction: As of 24 October 2021, 128,868 laboratory-confirmed COVID-19 cases and 3550 deaths were reported from Namibia. The national COVID-19 vaccination campaign that started in March 2021 included health workers (HWs) as a priority group. The vaccines most administered were Sinopharm, AstraZeneca, Pfizer-BioNtech, and Janssen.
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