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Cardiopulmonary exercise capacity markers and their link to symptom burden in patients at risk for heart failure with non-reduced ejection fraction.
Sci Rep
March 2025
Sports Medicine Outpatient Clinic, University Leipzig, Leipzig, Germany.
The American Heart Association (AHA) guidelines assess heart failure (HF) via comorbidities, laboratory markers, and echocardiography, while the New York Heart Association (NYHA) classification evaluates functional capacity. The primary objective of this study was to investigate the correlation between objectified HF-related symptoms and cardiac and muscular exercise capacity in Stage B HF patients with non-reduced ejection fraction. As secondary endpoints, we stratified this analysis for subgroups of NYHA classes to evaluate the primary endpoint for different levels of impairment and for sex to address for differences between men and women.
View Article and Find Full Text PDFFertility attitudes and intentions among postgraduate female and male students in China: A qualitative focus group study.
Sex Reprod Healthc
March 2025
Department of Nursing, Chengde Medical University, Anyuan Road, Shuangqiao District City of Chengde Hebei Province, China. Electronic address:
Objective: To explore the fertility attitudes and intentions of postgraduate female and male students in China.
Methods: A qualitative descriptive study was conducted using focus group interviews and purposive sampling to select 27 postgraduate students. This diverse group included eight nursing, five pharmacy, four rehabilitation, four ophthalmology, and six stomatology students from a graduate school in China.
Trends in stroke mortality in Latin America and the Caribbean from 1997 to 2020 and predictions to 2035: An analysis of gender, and geographical disparities.
J Stroke Cerebrovasc Dis
March 2025
Facultad de Medicina, Universidad Nacional San Luis Gonzaga de Ica, Ica, Peru.. Electronic address:
Background: Stroke is a leading cause of death and disability globally, with significant public health implications. In Latin America, while mortality rates have declined, the number of stroke cases has increased due to prevalent risk factors like high blood pressure and obesity. Unlike Europe, recent trends in stroke mortality in this region remain underreported.
View Article and Find Full Text PDFResearch progress on estrogen and estrogen receptors in the occurrence and progression of autoimmune thyroid diseases.
Autoimmun Rev
March 2025
Department of Endocrinology, Shengjing Hospital of China Medical University, Shenyang, Liaoning Province, PR China. Electronic address:
Autoimmune thyroid disease (AITD) is a category of disease related to sex differences, with a significantly higher incidence in women than in men. In addition to X chromosome inactivation abnormalities, Estrogen and estrogen receptors may lead to the sex differences in AITD. Estrogen, estrogen receptors and estrogen receptor-mediated signaling pathways can affect the number and function of immune cells and the function of the thyroid to promote the development of AITD.
View Article and Find Full Text PDFSex Hormones and Heart Failure Risk.
JACC Adv
March 2025
Division of Cardiology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Heart failure (HF) is a significant cause of morbidity and mortality. Although there are inconsistencies, epidemiological studies have implicated sex hormones (SHs) in pathways that are linked to HF. The age-related decline in SH levels causes physiological changes that differentially impact HF risk in both sexes.
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