Aim: to study the clinical and morphological manifestations of portal gastropathy in patients with liver cirrhosis (LC).
Subjects And Methods: One hundred and sixty-nine patients with Child-Pugh Classes B and C CL and 150 patients with gastritis and peptic ulcer disease without LC were examined. All the patients underwent fibrogastroscopy and morphological study of the gastric mucosa (GM). Morphological and serological studies detected Helicobacter pylori in all the patients.
Results: The endoscopic signs of portal gastropathy were found in 46.7-50.9% of the patients with LC; dilated capillaries and microbleedings in the GM were recorded in 73.9-83.7%. Ulcerative and erosive defects of the gastroduodenal area were identified in 31.9% of the patients with CL and these were accompanied by nemorrhages in 50% of cases. In patients with ulcers and erosions, the diameter of capillaries in different gastric portions was 23-56% larger than that in patients without these abnormalities. There was a significant direct correlation between the presence of H. pylori IgG and the morphological signs of portal gastropathy in the antrum.
Conclusion: An association was found between the signs of portal gastropathy and the presence of ulcerative and erosive defects in the gastroduodenal area in patients with LC.
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