During the period from 2001 to 2005 operations were performed on 186 patients with locally-spread colorectal cancer. In 132 cases (the 1st group) radical combined resections were performed, 54 patients (the 2nd group) underwent palliative operations. The morbidity rate was 18.2% (24 cases) in the first group and 7.4% (4 cases) in the second group. The mortality rate in the first group was 2.3% (3 cases), no mortality was observed in the second group. Overall 3-year survival in the first group was 69.9%, and no one patient of the second group survived longer than 3 years. Overall 5-year survival in the first group was 54.7%, and the relapse-free 5-year survival was 52.8%. The data obtained have shown the effectiveness of combined resections in treatment of locally-spread colorectal cancer. We suggest that further improvement of long-term results can be achieved using chemoradiation.

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