Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1021/cr900395y | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Inspiring basic and applied research in genome integrity mechanisms: Dedication to Samuel H. Wilson.
Environ Mol Mutagen
April 2024
Department of Pathology and Laboratory Medicine and Legorreta Cancer Center, Brown University, Providence, Rhode Island, USA.
Article Synopsis
- This Special Issue (SI) of Environmental and Molecular Mutagenesis focuses on recent findings related to genome integrity mechanisms, highlighting their significance in basic and environmental health sciences.
- The issue includes a mix of research articles and reviews from both established scientists and emerging researchers, covering topics like DNA repair mechanisms and key enzymes involved in these processes.
- Additionally, it features analyses of DNA damage caused by environmental mutagens, providing insights into the effects of agents like UV light and aflatoxin on DNA mutations.
Research updates and progress on nutritional significance of the amides I and II, alpha-helix and beta-sheet ratios, microbial protein synthesis, and steam pressure toasting condition with globar and synchrotron molecular microspectroscopic techniques with chemometrics.
Crit Rev Food Sci Nutr
December 2024
Department of Animal and Poultry Science, College of Agriculture and Bioresources, University of Saskatchewan, Saskatoon, Canada.
This article aims to review research updates and progress on the nutritional significance of the amides I and II, the alpha-helix and beta-sheet ratios, the microbial protein synthesis, and the steam pressure toasting condition in food and feed with globar and synchrotron molecular microspectroscopic techniques plus chemometrics (both univariate and multivariate techniques). The review focused on (I) impact of the amides I and II, and the alpha-helix and beta-sheet-structure ratios in food and feeds; (II) Current research progress and update in synchrotron technique and application in feed and food molecular structure studies that are associated with nutrition delivery; (III) Impact of thermal processing- steam pressure toasting condition on feed and food; (IV). Impact of the microbial protein synthesis and methodology on feed and food; and (V).
View Article and Find Full Text PDFUpdated efficacy and safety of KEYNOTE-224: a phase II study of pembrolizumab in patients with advanced hepatocellular carcinoma previously treated with sorafenib.
Eur J Cancer
May 2022
Massachusetts General Hospital Cancer Center and Harvard Medical School, 55 Fruit Street, Boston, MA, USA; Jiahui International Cancer Center, Jiahui Health, Shanghai, China. Electronic address:
Objective: Pembrolizumab, a PD-1 inhibitor, demonstrated anti-tumour activity and tolerability in patients treated with sorafenib and with advanced hepatocellular carcinoma in KEYNOTE-224. Longer-term efficacy and safety after ∼2.5 years of additional follow-up are reported.
View Article and Find Full Text PDFOn the border of the amyloidogenic sequences: prefix analysis of the parallel beta sheets in the PDB_Amyloid collection.
J Integr Bioinform
July 2021
PIT Bioinformatics Group, Eötvös University, Budapest H-1117, Hungary.
The Protein Data Bank (PDB) today contains more than 174,000 entries with the 3-dimensional structures of biological macromolecules. Using the rich resources of this repository, it is possible identifying subsets with specific, interesting properties for different applications. Our research group prepared an automatically updated list of amyloid- and probably amyloidogenic molecules, the PDB_Amyloid collection, which is freely available at the address http://pitgroup.
View Article and Find Full Text PDFInsights into modular polyketide synthase loops aided by repetitive sequences.
Proteins
September 2021
Department of Molecular Biosciences, The University of Texas at Austin, Austin, Texas, USA.
The loops of modular polyketide synthases (PKSs) serve diverse functions but are largely uncharacterized. They frequently contain amino acid repeats resulting from genetic events such as slipped-strand mispairing. Determining the tolerance of loops to amino acid changes would aid in understanding and engineering these multidomain molecule factories.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!