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Tile-Based Pairwise Analysis of GC × GC-TOFMS Data to Facilitate Analyte Discovery and Mass Spectrum Purification.
Anal Chem
April 2022
Department of Chemistry, University of Washington, Box 351700, Seattle, Washington 98195-1700, United States.
A new tile-based pairwise analysis workflow, termed 1v1 analysis, is presented to discover and identify analytes that differentiate two chromatograms collected using comprehensive two-dimensional (2D) gas chromatography coupled with time-of-flight mass spectrometry (GC × GC-TOFMS). Tile-based 1v1 analysis easily discovered all 18 non-native analytes spiked in diesel fuel within the top 30 hits, outperforming standard pairwise chromatographic analyses. However, eight spiked analytes could not be identified with multivariate curve resolution-alternating least-squares (MCR-ALS) nor parallel factor analysis (PARAFAC) due to background contamination.
View Article and Find Full Text PDFSustainability Perspectives of L. Walp. Cultivation under No Tillage and Water Stress Conditions.
Plants (Basel)
December 2019
Department of Biotechnology and Bioscience, University of Milan-Bicocca, Piazza della Scienza 2, 20126 Milano, Italy.
Article Synopsis
- Agriculture faces challenges from climate change, leading to unpredictable weather and water shortages in crop production, especially in developing countries.
- Conservation agriculture (CA) offers a sustainable approach with benefits like reduced tillage, cover crops, and crop rotation, aiming to increase crop yields and lessen environmental impact.
- A study on cowpea growth showed that while conventional tillage (CT) led to faster initial growth, no-tillage (NT) management increased adaptability and yield over time, with minimal effects on the nutritional quality of the beans.
Pharmacogenomics: Precision Pharmacy in 503A Compounding.
Int J Pharm Compd
August 2018
International Journal of Pharmaceutical Compounding.
The first recorded mention of a pharmacogenomic response may be that of Pythagoras in 510 BC, when he noted that hemolytic anemia developed in some but not all people who ingested fava beans. The application of such accounts to pharmacotherapy was inevitable, and customized medications have been compounded since antiquity to treat the needs of individual patients. Today, advances in pharmacogenomic testing yield results that enable more effective targeted therapies sooner in the course of treatment, prevent drug-related adverse effects, save cost, and ensure a better therapeutic outcome.
View Article and Find Full Text PDFScience and Culture: Artistic endeavors strive to save coral reefs.
Proc Natl Acad Sci U S A
May 2018
Remote health monitoring (RHM) systems are becoming more widely adopted by clinicians and hospitals to remotely monitor and communicate with patients while optimizing clinician time, decreasing hospital costs, and improving quality of care. In the Women's heart health study (WHHS), we developed Wanda-cardiovascular disease (CVD), where participants received healthy lifestyle education followed by six months of technology support and reinforcement. Wanda-CVD is a smartphone-based RHM system designed to assist participants in reducing identified CVD risk factors through wireless coaching using feedback and prompts as social support.
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