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Wernicke Encephalopathy Presenting With Syndrome of Inappropriate Antidiuretic Hormone.
Pediatr Neurol
December 2024
University of Alabama, Birmingham, Children's of Alabama, Birmingham, Alabama.
Wernicke encephalopathy is a well-described neurological complication of thiamine deficiency that is classically characterized by a triad of mental confusion, ophthalmoplegia, and gait ataxia. Although most commonly linked to alcoholism and thiamine deficiency in adults, it can present in pediatric patients. Wernicke encephalopathy presenting as dysnatremias is not well described.
View Article and Find Full Text PDFUpdate on perioperative fluids.
Best Pract Res Clin Anaesthesiol
June 2024
Department of Anesthesiology and Intensive Care Medicine, University Hospital of Tuebingen, Hoppe-Seyler-Straße 3, 72076, Tübingen, Germany.
Adequate fluid management in the perioperative period in paediatric patients is essential for restoring and maintaining homeostasis and ensuring adequate tissue perfusion. A well-designed infusion regimen is crucial for preventing severe complications such as hyponatraemic encephalopathies. The composition of perioperative fluid solutions is now guided by an understanding of extracellular fluid physiology.
View Article and Find Full Text PDFExercise-Associated Hyponatremic Encephalopathy, Rhabdomyolysis, and Acute Kidney Injury While Hiking in the Grand Canyon.
Wilderness Environ Med
December 2024
University of Arizona College of Medicine, Phoenix, AZ, USA.
Article Synopsis
- A 41-year-old male hiker experienced a serious medical emergency after consuming too much water while hiking in the Grand Canyon during hot weather, leading to multiple health issues.
- He suffered from exercise-associated hyponatremic encephalopathy (EAHE), exertional rhabdomyolysis (ER), and acute kidney injury (AKI), which resulted in severe pain, disorientation, and a grand mal seizure during helicopter evacuation.
- The case highlights the dangers of excessive water intake, potential complications from strenuous exercise, and the need for prompt treatment of life-threatening conditions like EAHE and compartment syndromes.
Frequency and severity of hyponatremia in healthy children with acute illness.
Pediatr Nephrol
March 2025
Department of Nephrology and Rheumatology, Tokyo Metropolitan Children's Medical Center, 2-8-29 Musashidai, Fuchu, Tokyo, 183-8561, Japan.
Article Synopsis
- Hyponatremia is a condition marked by low sodium levels and can occur during the acute phase of many illnesses, but its prevalence and severity in various medical situations is not fully understood.
- A study at Tokyo Metropolitan Children's Medical Center reviewed 2,717 urgent pediatric admissions and found that 260 (13.8%) had hyponatremia, with type 1 diabetes being the most common associated condition (69%).
- The research highlighted significant hyponatremia in conditions like Kawasaki disease and acute infectious encephalopathy, but noted that conditions like acute bronchial asthma or fractures rarely showed low sodium levels upon arrival.
A Case of Hyponatremic Hypertensive Syndrome With Neurologic Sequelae Secondary to Unilateral Renal Artery Stenosis.
Cureus
September 2024
Internal Medicine, Dayton Veteran's Affairs Medical Center (Wright State University Internal Medicine Associate Faculty), Dayton, USA.
Article Synopsis
- Unilateral renal artery stenosis can lead to a rare and serious condition known as hyponatremic hypertensive syndrome (HHS), which presents with low sodium levels and high blood pressure.
- A case study highlights a 62-year-old man experiencing HHS during a hypertensive emergency complicated by encephalopathy.
- Early diagnosis and management focusing on fluid and electrolyte balance are crucial to reduce complications and enhance patient outcomes.
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