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Association between the onset of diabetic retinopathy and thickness changes in the retina and choroid of children with type 1 diabetes: A three-year longitudinal study.
Ophthalmic Physiol Opt
January 2025
Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Purpose: To explore the longitudinal changes in retinal and choroidal thickness and their relation with the onset of type 1 diabetes mellitus (T1DM) in children.
Methods: Thirty-eight children with T1DM and 71 healthy controls were included in this 3-year longitudinal study. Ophthalmic and systemic examinations were conducted on each participant.
Perivascular Chorioretinal Atrophy: an Unusual Feature in Pathologic Myopia Eyes.
Am J Ophthalmol
December 2024
Department of Ophthalmology, New Civil Hospital, Strasbourg University Hospital, FMTS, Strasbourg, France. Electronic address:
Purpose: To describe a new feature in pathologic myopia: perivascular patchy chorioretinal atrophy (PVCA) DESIGN: Cross-sectional study METHODS: 604 eyes of 312 highly myopic patients followed at Strasbourg University Hospitals were reviewed for the presence of PVCA lesions. Demographic, clinical, and paraclinical data (ultra-widefield retinography, optical coherence tomography (OCT), fluorescein and indocyanine green angiography images) were analyzed. Controls were matched for age, sex, and axial length (AL).
View Article and Find Full Text PDFCHOROIDAL VASCULAR PARAMETERS IN OCULAR ROSACEA PATIENTS.
Photodiagnosis Photodyn Ther
December 2024
Department of Medicine, Surgery and Dentistry "Scuola Medica Salernitana", University of Salerno, Baronissi, SA, Italy.
circSIRT2/miR-542-3p/VASH1 axis regulates endothelial-to-mesenchymal transition (EndMT) in subretinal fibrosis in age-related macular degeneration models.
Aging Cell
January 2025
Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University, School of Medicine, Shanghai, China.
Neovascular age-related macular degeneration (nAMD), characterized by choroidal neovascularization (CNV), is one of the leading causes of severe visual impairment and irreversible vision loss around the world. Subretinal fibrosis (SRF) contributes to the incomplete response to anti-vascular endothelial growth factor (VEGF) treatment and is one of the main reasons for long-term poor visual outcomes in nAMD. Reducing SRF is urgently needed in the anti-VEGF era.
View Article and Find Full Text PDFMultifocal Torpedo Maculopathy Complicated by Choroidal Neovascularization.
J Vitreoretin Dis
December 2024
Associated Retinal Consultants, Royal Oak, MI, USA.
To present a pediatric patient with a unique configuration of torpedo maculopathy complicated by macular choroidal neovascularization (CNV). A single case was retrospectively reviewed. An 8-year-old male child presented with decreased vision in the left eye and was found to have 2 distinct torpedo maculopathy lesions, 1 a smaller hypopigmented lesion in the temporal parafovea and the other a larger hyperpigmented comet-shaped lesion in the temporal periphery.
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