Different extracts of leaf parts of Wrightia tinctoria and fruit powder of Morinda citrifolia have been studied against replication of HIV-1(IIIB) in MT-4 cells and HCV in Huh 5.2 cells. Chloroform extract of Wrightia tinctoria exhibited a maximum protection of 48% against the cytopathic effect of HIV-1(IIIB) in MT-4 cells. Fruit juice of Morinda citrifolia exhibited a displayed marked cytotoxic activity in lymphocyte (MT-4) cells (CC50: 0.19 mg/ml). The 50% effective concentration for inhibition of HCV subgenomic replicon replication in Huh 5-2 cells by Morinda citrifolia was 0.98 mug/ml and by chloroform extract of Wrightia tinctoria was 10 mug/ml. The concentration that reduced the growth of exponentially proliferating Huh 5-2 cells by 50% was greater than 50 mug/ml.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2846473 | PMC |
| http://dx.doi.org/10.4103/0250-474X.59550 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Evaluation of anti-cancer potential and apoptotic profile of ethanolic plant extract of against oral cancer cell line.
J Oral Maxillofac Pathol
July 2024
Department of Oral and Maxillofacial Pathology and Microbiology, SRM Kattankulathur, Dental College and Hospital- SRMIST, Chengalpattu, Tamil Nadu, India.
Background: For decades, () has been important in the field of traditional medicine. The identification and isolation of numerous chemically potent and pharmaceutically advantageous phytochemicals isolated from this plant extract has contributed to its resurrection into evidence-based modern medicine. This plant is inexpensive and indigenous to the Indian subcontinent.
View Article and Find Full Text PDFAnti-psoriatic potential of medicinal plants, Alstonia scholaris, Wrightia tinctoria, and Solanum xanthocarpum, using human HaCaT keratinocytes by multi-parametric analysis.
J Ethnopharmacol
November 2024
Amity Institute of Virology and Immunology, Amity University Uttar Pradesh, Sec-125, Noida, Uttar Pradesh, India. Electronic address:
Ethnopharmacological Relevance: Psoriasis, a widespread skin condition impacting over 100 million individuals globally, is characterised by uncontrolled hyperproliferation of keratinocytes, abnormal apoptosis, and excessive secretion of inflammatory cytokines and angiogenic factors. Traditional use of Alstonia scholaris (L.) R.
View Article and Find Full Text PDFHerbal Composite Preparation and Investigating its Efficiency to Inhibit Biofilm Formation and Virulence Factors of and - Formulation of Mouthwash Using a Herbal Composite and Evaluating its Anti-microbial Activity.
J Pharm Bioallied Sci
April 2024
Department of Conservative Dental Sciences, College of Dentistry, Faculty of Dentistry, Jazan University, KSA.
Herbal composite preparation was studied with the aim of inhibiting the virulence factors of two dental pathogens: and . A novel herbal composite was developed using the herbal extracts of and . During the study, the following observations were noted.
View Article and Find Full Text PDF"Purplish Blue" or "Greenish Grey"? Indigo Qualities and Extraction Yields from Six Species.
Plants (Basel)
March 2024
Institute of Animal Nutrition and Functional Plant Compounds, Department Farm Animals and Veterinary Public Health, University of Veterinary Medicine, Vienna, Veterinärplatz 1, 1210 Vienna, Austria.
Indigo quality is determined by its indigotin content. Another quality indicator is colour. For an evaluation of species, indigo samples from , , , , and cultivated in Austria and China were visually classified and analysed spectrophotometrically and using a L*a*b* measuring device.
View Article and Find Full Text PDFIn the semi-arid plains of Southern India, outside the protected area network, sacred groves forests and the barren lands invaded by Prosopis juliflora are reckoned to be the major greenery, but have homogenous and heterogeneous vegetation respectively. This study attempted to compare 50 Sacred Groves Stands (SGS) and 50 monodominant Prosopis juliflora Stands (PJS) for the functional diversity, evenness, floral diversity, carbon stock and dynamics, carbon-fixing traits, dendrochronology of trees, soil nutrient profiles, and soil erosion. Quadrat sample survey was adopted to record stand density, species richness, abundance, basal area and leaf area index; composite soil samples were collected at depths 0-30 cm for nutrient profiling (N, P, K, and OC).
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!