In the pediatric population, cutis aplasia, scalp avulsion, and burn injuries are the leading causes of scalp alopecia that is evaluated for reconstruction by plastic surgeons. Scalp alopecia is seen in 25% of children who suffer burn injuries of the head and neck. These injuries are rarely isolated to the scalp, and the adjacent structures are often affected. This may complicate reconstruction surgery and necessitate multiple reconstructive procedures. A retrospective chart was performed of all cases of staged scalp tissue-expansion cases performed for the reconstruction of burn-related scalp alopecia by the two senior authors at the Shriner's Hospital for Children of Boston between 2003 and 2007. In each case, the incidence and severity of burn-related deformities of the nose, eyebrows, and ears as seen in clinical photographs were documented. Between 2003 and 2007, 96 scalp tissue expanders were placed in 78 patients for the treatment of scalp alopecia. Of these patients, associated adjacent burn deformities were commonly found involving the ear, nose, and eyebrow. These injuries included ear deformity (46%), nasal deformity (27%), and eyebrow deformity (46%). In planning the surgical reconstruction for pediatric scalp alopecia, it is helpful to evaluate each patient for adjacent structure burn injuries requiring reconstruction. It is our belief that the stages of tissue expansion surgery can be combined with the reconstruction of associated burn injuries sometimes using the region of expected alopecia excision.
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http://dx.doi.org/10.1097/BCR.0b013e3181db51f9 | DOI Listing |
Indian J Sex Transm Dis AIDS
December 2024
Department of Dermatology, Venereology and Leprosy, Sri Manakula Vinayagar Medical College and Hospital, Puducherry, India.
Alopecia is usually an overlooked manifestation of syphilis commonly seen in secondary syphilis with a prevalence of 2.9%-7%. It is broadly classified into symptomatic and essential alopecia and the observed patterns include moth-eaten type, generalized thinning, and mixed pattern.
View Article and Find Full Text PDFJ Cutan Med Surg
January 2025
Department of Dermatology, Venereology and Leprology, Sundaram Hospital, Trichy, Tamil Nadu, India.
Background: Intralesional (IL) steroids are the first-line treatment option for localized alopecia areata (AA). The present study aimed to compare the efficacy of topical calcipotriol with IL triamcinolone acetonide versus IL triamcinolone acetonide alone in AA.
Methods: This randomized single-blinded clinical trial was conducted in a dermatology outpatient department.
Front Pediatr
January 2025
Department of Dermatology, The First Affiliated Hospital of Ningbo University, Ningbo, Zhejiang Province, China.
Int J Pharm
January 2025
School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 51006 China. Electronic address:
Androgenic alopecia (AGA), the most prevalent type of progressive hair loss, currently lacks an effective topical treatment regimen. In this study, we synthesized an ionic liquid (IL) to co-solubilize minoxidil (MXD) and finasteride (FIN) and subsequently formulated them into an in situ thermosensitive ionic liquid/cyclodextrin/poloxamer hydrogel (ICPG), termed M + F@ICPG. M + F@ICPG was developed for the transdermal co-delivery of these two drugs, aiming to provide a multipath therapeutic approach for AGA while avoiding the adverse effects commonly associated with oral FIN and topical MXD tincture.
View Article and Find Full Text PDFJ Am Acad Dermatol
January 2025
Dr. Phillip Frost Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL, 33133, USA.
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