The confines of this chapter are necessarily arbitrary. Its limits are partly imposed by the extent of my reading (all the references have been read in full!) and partly by the restrictions of space - as a consequence of that restriction there are innumerable examples which I have been unable to cover. I have concentrated, though not exclusively, on the literature of the 19th century. There is much neurology in the modern novel, but the accessibility afforded by the internet and other sources to accounts of neurological symptoms and diseases allows a present-day author an access that can bypass personal experience. Of greater interest are those descriptions of neurological disorders which coincided with, or even ante-dated, their appearance in the medical literature. My reading has been in English, but has extended to works translated from Spanish, French, German and Russian. I have concentrated on a small group of neurological conditions whose descriptions are of particular interest in the depth of observation they display, a depth suggesting they have stemmed from first-hand experience. They are grouped under the headings of cerebrovascular disease, syncopal attacks and epilepsy.
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AJNR Am J Neuroradiol
January 2025
From the Department of Neurosurgery (D.N., L.H., J.G., T.P., R.T.S., A.R., C.M.J.); Department of Neuroradiology (T.D., E.I.P.), Institute of Diagnostic and Interventional Neuroradiology, and Department of Neurology (C.S.), Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland. Department of Neurosurgery (J.B.), Medical Center, University of Freiburg, Freiburg, Germany.
Background And Purpose: In patients diagnosed with spontaneous intracranial hypotension (SIH), microspurs are considered the culprit lesion in most ventral dural leaks (type I). The imaging characteristics of discogenic spurs, and their prevalence in the general population has not been reported in the literature.
Materials And Methods: This observational case-control study was conducted comparing the prevalence and characteristics of discogenic microspurs between SIH patients with a type I leak treated at a tertiary hospital between 2013 and 2023 and an age-and sex matched cohort of trauma patients.
Zhong Nan Da Xue Xue Bao Yi Xue Ban
August 2024
Department of Neurology, Second Xiangya Hospital, Central South University, Changsha 410011.
Methylenetetrahydrofolate reductase (MTHFR) deficiency is a rare autosomal recessive genetic disorder caused by mutations in the gene, leading to a variety of clinical manifestations. In October 2022, the Second Xiangya Hospital of Central South University admitted a 21-year-old male patient with neuropsychiatric disorders, presenting primarily with cognitive decline, limb tremors, abnormal mental and behavioral symptoms, seizures, and gait disturbances. These symptoms had gradually developed over 5 years, worsening significantly in the past year.
View Article and Find Full Text PDFBMJ Open
January 2025
School of Behavioural, Social and Legal Sciences, Örebro University, Orebro, Sweden.
Introduction: Traumatic brain injury (TBI) is a global health issue and a leading cause of long-term disabilities and mortality worldwide. There is growing evidence that TBI rehabilitation should be differentiated and individualised according to gender to provide more effective healthcare and rehabilitation. However, there is a lack of reviews focusing on the rehabilitation for women with TBI and there is a need to summarise existing knowledge to guide and individualise their rehabilitation.
View Article and Find Full Text PDFDev Cogn Neurosci
December 2024
Division of Psychology and Language Sciences, UCL, London WC1H 0AP, UK. Electronic address:
Executive functions can be classified into processes of inhibition, working memory and shifting, which together support flexible and goal-directed behaviour and are crucial for both current and later-life outcomes. A large body of literature has identified distinct brain regions critical to performing each of these functions. These findings are however predicated on a piecemeal and single-task approach.
View Article and Find Full Text PDFPLoS One
January 2025
The Third Clinical Medical College, Zhejiang Chinese Medical University, Key Laboratory of Acupuncture and Neurology of Zhejiang Province, Hangzhou, China.
Background: Postoperative cognitive dysfunction (POCD) is associated with an increased risk of dementia and may lead to chronic neurodegeneration. The utilization of intraoperative Transcutaneous Electrical Acupoint Stimulation (TEAS) in conjunction with anesthesia is expected to become an effective preventive measure for POCD in clinical practice.
Methods: We conducted a comprehensive literature review focusing on the use of TEAS in the prevention of POCD during surgical anesthesia.
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