The association of malignancy with dermatomyositis is well known, and the frequency is reported to be up to 30%. However, cutaneous lymphoma associated with dermatomyositis has rarely been reported. We experienced a case of nasal-type NK/T-cell lymphoma in a 40-year-old woman with a 2-year history of dermatomyositis. To our knowledge, this is the first report of cutaneous involvement of nasal-type NK/T-cell lymphoma developing in a dermatomyositis patient. When skin lesions are resistant to aggressive conventional treatment in dermatomyositis patients, we should consider the possibility of malignancy, especially cutaneous lymphoma.
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http://dx.doi.org/10.1111/j.1756-185X.2009.01400.x | DOI Listing |
Respir Med Case Rep
September 2024
Department of Thoracic Oncology, Hefei Cancer Hospital, Chinese Academy of Sciences, No. 68 Yangqiao Road, Hefei, 230000, China.
Extranodal Natural Killer/T Cell Lymphoma Nasal Type (EN-NK/T-CL-NT) is a rare type of non-Hodgkin lymphoma in which the lesion is usually located in the upper respiratory tract, such as nasal cavity, palate, and nasopharynx. In addition, the primary lesion of EN-NK/T-CL-NT can rarely originate in extranasal sites such as the skin, gastrointestinal tract, testicles, central nervous system, and lungs. We describe an 82-year-old male smoker was brought to the hospital with 8 months of fever, cough, sputum production, chest pain, and chest tightness.
View Article and Find Full Text PDFWorld J Clin Oncol
August 2024
Department of Wound Repair, Key Laboratory of Emergency and Trauma of Ministry of Education, The First Affiliated Hospital of Hainan Medical University, Haikou 570102, Hainan Province, China.
Background: Non-Hodgkin's lymphoma (NHL) is a malignant tumor that originates from the lymphoid tissues and can potentially affect numerous organs within the body. Among these, the skin stands out as one of the primary sites affected by NHL, often presenting with multiple extra-nodal manifestations. In this report, we present an unusual case of NHL involving chronic wounds in the lower extremities that were difficult to heal.
View Article and Find Full Text PDFAnn Plast Surg
August 2024
From the Department of Plastic and Reconstructive Surgery, Zhongshan Hospital, Fudan University, Shanghai, China.
Background: Immunosuppressive therapy is essential for to prevent graft rejection in renal transplant patients; however, it is associated with elevating the risk of several pathologies in these patients particularly infectious and neoplastic conditions. In this study, we explore the diagnosis and treatment of skin lesions in renal transplant patients.
Methods: A retrospective chart review of 12 renal transplant recipients referred to plastic and reconstructive surgery with skin lesions from 2000 to 2020 was performed.
Cureus
June 2024
Central Laboratory of Virology, Ibn Sina Hospital, Faculty of Medicine and Pharmacy, Mohammed V University, Rabat, MAR.
J Clin Immunol
June 2024
Department of Clinical Immunology, Children's Hospital of Fudan University, National Children Medical Center, 399 Wanyuan Road, Shanghai, 201102, China.
Purpose: Moesin (MSN) deficiency is a recently reported combined immunodeficiency, and few cases have been reported to date. We describe a Chinese patient with a novel mutation causing MSN deficiency and a novel phenotype.
Methods: Clinical and immunological data were collected.
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