An efficient protocol for the synthesis of a range of 1,2-benzisoxazoles using an improved 1,3-dipolar cycloaddition of nitrile oxides and benzyne is described. Key to the procedure is the in situ generation of the reactive nitrile oxide and benzyne reactants simultaneously.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1039/b927235f | DOI Listing |
Publication Analysis
Top Keywords
13-dipolar cycloaddition
8
nitrile oxides
8
oxides benzyne
8
efficient entry
4
entry 12-benzisoxazoles
4
12-benzisoxazoles 13-dipolar
4
cycloaddition situ
4
situ generated
4
generated nitrile
4
benzyne efficient
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!