AI Article Synopsis
- Phosphorus and sulfur ylides are used to efficiently synthesize specific compounds, namely 3-spirocyclopentene- and 3-spiropyrazole-2-oxindoles.
- The synthesis involves E- and Z-isomers of bromo derivatives of Morita-Baylis-Hillman adducts of isatin using certain chemical reagents.
- This process utilizes a [3 + 2]-annulation strategy, highlighting a novel approach in organic chemistry.
Article Abstract
The chemistry phosphorus and sulfur ylides have been exploited for a facile, short and efficient synthesis of 3-spirocyclopentene- and 3-spiropyrazole-2-oxindoles from E- and Z-isomers of bromo derivatives of Morita-Baylis-Hillman adducts of isatin with Ph(3)P/activated alkene/K(2)CO(3) and Me(2)S/DEAD/K(2)CO(3), respectively, via [3 + 2]-annulation strategy.
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Article Synopsis
- Phosphorus and sulfur ylides are used to efficiently synthesize specific compounds, namely 3-spirocyclopentene- and 3-spiropyrazole-2-oxindoles.
- The synthesis involves E- and Z-isomers of bromo derivatives of Morita-Baylis-Hillman adducts of isatin using certain chemical reagents.
- This process utilizes a [3 + 2]-annulation strategy, highlighting a novel approach in organic chemistry.
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