In the last 15 years, computer-assisted surgery (CAS) has been used for many purposes during anterior cruciate ligament (ACL) reconstruction, such as tunnel positioning, joint laxity evaluation, and biomechanical studies. This article is an evidence-based literature review of the contribution of such technology to ACL surgery. A search of the PubMed and Medline databases was performed. Articles were classified according to the study design and to the research topic: anatomy, laxity, kinematics, and comparison of surgical techniques. An evidence-based approach was used to verify the clinical usefulness of CAS to ACL surgery. The use of CAS for research purposes was also evaluated. CAS was shown to improve femoral tunnel positioning, even if clinical outcomes showed no differences compared with manual techniques. CAS technology was found to be useful for research purposes in terms of providing a better comprehension of the effect of different ACL reconstructions and of the different bundles on joint laxity, as well as describing tunnel positioning in relation to native ACL insertion. CAS in ACL surgery can improve results at time 0 and can improve knowledge about ACL anatomy and kinematics. Its application remains limited mostly to research purposes because of the invasiveness of the system and the absence of improved clinical results at follow-up.
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http://dx.doi.org/10.1016/j.arthro.2009.09.018 | DOI Listing |
J Hand Surg Asian Pac Vol
January 2025
Department of Orthopaedic Surgery, Graduate School of Medicine, Chiba University, Chiba, Japan.
Surgeons use anatomical landmarks like the scaphoid tubercle, pisiform, trapezial tubercle and hook of hamate, along with Kaplan cardinal line (KCL) to avoid injury to the recurrent motor branch (RMB) of the median nerve during carpal tunnel release. The presence of transverse muscle fibres (TMF) overlying the transverse carpal ligament (TCL) may suggest proximity of the RMB, but their anatomical relationship is unclear. In this study, we evaluated the accuracy of anatomical landmarks to the RMB, TMF origin and insertion, and examined the relationship between TMF presence and RMB running patterns.
View Article and Find Full Text PDFInt J Biol Macromol
January 2025
Laboratory of Medicinal Plant Biotechnology, College of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou, China; Jinhua Academy, Zhejiang Chinese Medical University, Jinhua 321015, China. Electronic address:
Benzylisoquinoline alkaloids (BIAs) are the primary active components of Stephania tetrandra. However, the molecular mechanisms underlying BIA biosynthesis in S. tetrandra remain poorly understood.
View Article and Find Full Text PDFTraffic Inj Prev
January 2025
School of Civil and Transportation Engineering, Guangdong University of Technology, Guangzhou, China.
Objective: The safety of highway tunnels hinges heavily on proper lighting infrastructure, yet luminaire failures pose an ongoing challenge. The study aims at assessing the impact of the locations of luminaire failures on highway tunnels safety.
Methods: The research involved conducting 300 on-site scenarios with 29 participants, with simulated drives in visual recognition experiments.
JBJS Essent Surg Tech
January 2025
The Ohio State University College of Medicine, Columbus, Ohio.
Background: An all-inside endoscopic flexor hallucis longus (FHL) tendon transfer is indicated for the treatment of chronic, full-thickness Achilles tendon defects. The aim of this procedure is to restore function of the gastrocnemius-soleus complex while avoiding the wound complications associated with open procedures.
Description: This procedure can be performed through 2 endoscopic portals, a posteromedial portal (the working portal) and a posterolateral portal (the visualization portal).
J Phycol
January 2025
Department of Food & Bioproduct Sciences, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.
Delta-6 fatty acid desaturases, which play key roles in the biosynthesis of polyunsaturated fatty acids (PUFAs), are membrane-associated enzymes that present significant challenges for isolation and purification, complicating their structural characterization. Here we report the identification and structure-function analysis of a novel Δ6 fatty acid desaturase (PmD6) from the marine alga Prorocentrum micans with substrate preference to α-linolenic acid (18:3n-3). Structural modeling revealed a mushroom-like structure of PmD6 formed by four transmembrane α-helices as a stem and three cytoplasmic domains as a cap.
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