[Extended preoperative course of radiotherapy as component of combined and complex treatment of locally-advanced ampular rectal cancer].

Sixty-two patients were treated for locally-advanced ampular rectal cancer at the Center's Clinic (2004-2008). Extended preoperative course of radiotherapy plus 5 = fluorouracil chemomodification was given to 55 patients (group 1) and the same plus hyperthermia--to 27 (group 2). Radiation injuries were reported in 37.1% (group 1) and 29.6% in group 2. Surgical complications occurred in 10 (group 1) (32.2%) and 8 (group 2) (32%). Relapse was registered in 3 (group 1) (12.5%) and 3 (group 2) (13.6%). Overall 3-year survival (group 1)--82%; (group 2)--63.9%; 3-year relapse-free survival (group 1)--69.8%; (group 2)--52.2%.