Background: The authors report the morphological and neuroimaging findings of an immature human fossil (Cranium 14) diagnosed with left lambdoid synostosis.
Discussion: The skull was recovered at the Sima de los Huesos site in Atapuerca (Burgos, Spain). Since the human fossil remains from this site have been dated to a minimum age of 530,000 years, this skull represents the earliest evidence of craniosynostosis occurring in a hominid. A brief historical review of craniosynostosis and cranial deformation is provided.
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http://dx.doi.org/10.1007/s00381-010-1133-y | DOI Listing |
J Clin Med
December 2024
Department and Clinic of Rheumatology, Rehabilitation and Internal Diseases, Poznan University of Medical Sciences, 28 Czerwca 1956 r. 135/147, 61-545 Poznań, Poland.
DDX3X syndrome is often misdiagnosed as autism spectrum disorder (ASD, Rett Syndrome, and Dandy-Walker Syndrome). Precise phenotyping is needed with reference to neurodevelopmental diagnosis. Observation of behavior and communication in parents with DDX3X syndrome in the USA, France, and Poland; conversations with the parents of patients; and rudimentary information in evidence-based medical articles prompted us to identify differences in communication, play, and social interaction between children with ASD only, those with both ASD and , and those with only.
View Article and Find Full Text PDFAnimals (Basel)
December 2024
MERAGEM (AGR-158) Research Group, Department of Genetics, University of Córdoba, CN IV KM 396, 14014 Cordoba, Spain.
The Spanish Merino is the most significant sheep breed globally due to its economic and cultural importance in human history. It has also had a substantial influence on the development of other Merino and Merino-derived breeds. Historical sources indicate that crossbreeding to produce finer, higher-quality wool was already taking place in the south of the Iberian Peninsula during the Roman era.
View Article and Find Full Text PDFThe rate of input of new genetic mutations, and the rate at which that variation is reshuffled, are key evolutionary processes shaping genomic diversity. Importantly, these rates vary not just across populations and species, but also across individual genomes. Despite previous studies having demonstrated that failing to account for rate heterogeneity across the genome can bias the inference of both selective and neutral population genetic processes, mutation and recombination rate maps have to date only been generated for a relatively small number of organisms.
View Article and Find Full Text PDFSci Prog
January 2025
Grupo de Nutrición, Facultad de Salud, Universidad del Valle, Cali, Colombia.
Objective: The expansion of human activities in northern Colombia has increased human-snake encounters, particularly with venomous . Given the limited knowledge of systemic envenomation effects and previous studies focusing only on early murine symptoms, this investigation aimed to describe the time-course physiopathology of envenomation following intramuscular injection .
Methods: Venom was inoculated in the gastrocnemius muscles of Swiss Webster mice, and blood, urine, and tissue samples were taken at different times to evaluate lethality and biochemical markers of renal function and oxidative stress.
Paleobiodivers Paleoenviron
May 2024
Hessisches Landesmuseum Darmstadt, Department of Natural History, Friedensplatz 1, 64283 Darmstadt, Germany.
The association of pollinators with their host plants is a critical element of ecosystem functioning and one that is usually determined indirectly in the fossil record from specific morphological traits of flowers or putative pollinating animals. The exceptionally fine preservation at Messel, Germany, offers an excellent source of data on pollen from fossil flowers as well as preserved adhering to insects as direct evidence of their association with specific floral lineages. Here, we report on pollen recovered from the body and legs of a large carpenter bee (Apidae: Xylocopinae: Xylocopini) from the Eocene of Messel.
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