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Oral Tranexamic Acid Treats Papulopustular Rosacea by Improving the Skin Barrier: Correspondence.
J Cosmet Dermatol
January 2025
Department of Dermatology, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Assessing Use and Familiarity of Enhanced Recovery After Surgery Elements in Pediatric Orthognathic Surgery.
J Craniofac Surg
January 2025
Department of Plastic Surgery, University of California, Irvine.
Enhanced recovery after surgery (ERAS) protocols have informed perioperative care across multiple surgical specialties, optimizing patient outcomes through surgical stress management and accelerated recovery. This study evaluates the familiarity and adoption of ERAS elements among craniofacial and oral and maxillofacial surgeons in pediatric orthognathic surgery, a field where a formal ERAS protocol has not been established. A closed-ended survey of 102 surgeons was conducted to assess familiarity with and utilization of 14 ERAS elements.
View Article and Find Full Text PDFTranexamic Acid in Symptomatic Chronic Subdural Hematoma in the Absence of Surgical Intervention.
Neurol India
November 2024
Department of Pharmacology, Kasturba Medical College, Manipal, Manipal Academy of Higher Education (MAHE) Manipal, Karnataka, India.
Background: Standard treatment for symptomatic chronic subdural hematoma (CSDH) is a burr-hole evacuation. However, in patients in whom surgical evacuation carries a very high risk, we do not have an established practice guideline.
Objective: To analyze the outcome of symptomatic CSDH treated only by tranexamic acid.
Hereditary hemorrhagic telangiectasia: A pediatric-focused review.
Semin Pediatr Neurol
December 2024
Department of Pediatrics, University of Pittsburgh Medical Center, Children's Hospital of Pittsburgh, United States. Electronic address:
Article Synopsis
- Clinical manifestations of hereditary hemorrhagic telangiectasia (HHT) involve vascular malformations affecting various organs, increasing the risk of bleeding and related complications.
- Diagnosis is based on the Curaçao criteria, which includes symptoms like nosebleeds and family history, and most patients carry pathogenic variants in specific genes.
- While there is no cure for HHT, treatment options focus on managing complications, including medication and, in some cases, surgical interventions when deemed necessary.
Tranexamic Acid is Associated With Reduced Blood Loss and Transfusion Requirement in Pediatric Midface Reconstruction.
J Oral Maxillofac Surg
November 2024
Director, Jaw Deformities Care Program, Attending Surgeon, Division of Plastic and Maxillofacial Surgery, Children's Hospital Los Angeles, Los Angeles, CA; Director, Jaw Deformities Care Program, Attending Surgeon, Division of Plastic and Reconstructive Surgery, Keck School of Medicine of USC, Los Angeles, CA. Electronic address:
Article Synopsis
- The study investigates the effects of tranexamic acid (TXA) on blood loss and transfusion needs during midface reconstruction surgeries, given the significant risks of bleeding in these procedures.
- Conducted at Children's Hospital Los Angeles from 2010 to 2023, the retrospective cohort study analyzed data from 80 patients, categorizing them based on whether they received TXA or not.
- Key outcomes measured included intraoperative blood loss, transfusion requirements, complications, and length of hospital stay, with a focus on determining any statistically significant differences linked to TXA administration.
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