False-positive IgM serology in coccidioidomycosis.

J Clin Microbiol

Infection Prevention Program/Quality Management, John C. Lincoln Health Network, 2423 West Dunlap Avenue, Suite 100, Phoenix, AZ 85021, USA.

Published: June 2010

The clinical observation has been made that there might be an unacceptable number of false-positive enzyme immunoassay (EIA) test results for IgM among persons suspected of having coccidioidomycosis. Patients with a positive result for IgM by EIA are thought to have a diagnosis of acute coccidioidomycosis. However, this study found that 82% of patients with an IgM-positive and IgG-negative EIA result did not have coccidioidomycosis.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2884478PMC
http://dx.doi.org/10.1128/JCM.01843-09DOI Listing

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