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New diterpenoids from Caesalpinia species and their cytotoxic activity. | LitMetric
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New diterpenoids from Caesalpinia species and their cytotoxic activity.

Biswanath Das Yallamalla Srinivas Chithaluri Sudhakar Ibram Mahender Keetha Laxminarayana Parigi Raghavendar Reddy Tuniki Venugopal Raju Naga Mahesh Jakka Janapala Venkateswara Rao

Bioorg Med Chem Lett

Organic Chemistry Division-I, Indian Institute of Chemical Technology, Hyderabad 500 007, India.

Published: May 2010

Chemical investigation on Caesalpinia crista afforded two new diterpenoids, 6beta-cinnamoyloxy-7beta-acetoxyvouacapen-5alpha-ol and 6beta,7beta-dibenzoyloxyvouacapen-5alpha-ol and on Caesalpiniapulcherrima another new diterpenoid, 12-demethyl neocaesalpin F along with several known constituents. The structures of the new compounds were settled from their 1D and 2D NMR spectral data. The cytotoxicity of these compounds was measured on two different cancer cell lines.

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http://dx.doi.org/10.1016/j.bmcl.2010.03.048DOI Listing

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