Objective: To compare negative expiratory pressure (NEP) technique with conventional test in detecting expiratory flow limitation (EFL) in chronic obstructive pulmonary diseases (COPD) patients.
Methods: EFL was measured with NEP technique and conventional method respectively in 72 COPD patients;EFL was measured with NEP technique in 20 COPD patients who failed to perform conventional test.
Results: EFL was detected in 54 of the 72 COPD patients. NEP test was successfully performed on the 20 patients, and 19 of them were found with EFL. The level of forced expired volume in one second percentage (FEV(1)%) of the patients with 2-score group (46.92 +/- 12.74)% and 3-score group (33.35 +/- 8.96)% were significantly lower than that of the 1-score group (63.60 +/- 16.65)%. Area under curve of NEP technique and conventional test in ROC is 0.903 and 0.761 respectively.
Conclusions: As compared with conventional test, EFL detected with NEP technique is more reliable in evaluating dyspnea of COPD patients. It is simple and doesn't require any cooperation of the patients. NEP technique can be applied in COPD patients who fail to receive conventional test.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Anti-PD-1 and anti-PD-L1 antibodies for glioma.
Cochrane Database Syst Rev
January 2025
Saúde Baseada em Evidências, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, Brazil.
Background: Glioblastoma multiforme (GBM) is the most common and aggressive adult glioma (16-month median survival). Its immunosuppressive microenvironment limits the efficacy of immune checkpoint inhibitors (ICIs).
Objectives: To assess the effects of the ICIs antibodies anti-programmed cell death 1 (anti-PD-1) and anti-programmed cell death ligand 1 (anti-PD-L1) in treating adults with diffuse glioma.
Analgesic effect of Dahuang Fuzi Decoction in neuropathic pain through inhibiting TNF-α and PI3K-AKT signaling.
Front Neurosci
December 2024
Basic Medical School, Guizhou University of Traditional Chinese Medicine, Guiyang, Guizhou, China.
Background: Neuropathic pain (NeP) presents considerable challenges in terms of effective management and significantly impacts the quality of life for affected patients. The current treatment options for NeP are limited, highlighting the need for alternative therapeutic approaches. Dahuang Fuzi Decoction (DF), a formula from traditional Chinese medicine, has shown potential in relieving pain symptoms associated with various types of NeP.
View Article and Find Full Text PDFConcurrent Evaluation of Restless Leg Syndrome, Neuropathic Pain, and Quality of Life in Anti-neutrophil Cytoplasmic Antibody-Associated Vasculitis: Single-Center Data.
Cureus
November 2024
Division of Rheumatology, Department of Internal Medicine, Erciyes University Faculty of Medicine, Kayseri, TUR.
Objective This study aims to investigate the frequency of restless leg syndrome (RLS) and neuropathic pain (NeP) and their effects on the quality of life (QoL) of patients with anti-neutrophil cytoplasmic antibody-associated vasculitis (AAV). Methods The study included 30 patients with AAV and 30 healthy volunteers. Demographic and clinical parameters and laboratory data were recorded.
View Article and Find Full Text PDFElevated serum neprilysin levels in patients with chronic hepatitis C and metabolic dysfunction-associated steatotic liver disease: hepatic oxidative stress as an underlying mechanism.
Mol Biol Rep
December 2024
Department of Internal Medicine II, Hamamatsu University School of Medicine, 1-20-1 Handayama, Chuo-ku, Hamamatsu, Shizuoka, 431-3192, Japan.
Background: Neprilysin (NEP) is a metalloprotease that has become a therapeutic target for the treatment of heart failure and hypertension. However, the significance of NEP in chronic liver diseases has rarely been investigated. In this study, we investigated the serum NEP levels in patients with chronic liver disease and their relationship with clinical parameters.
View Article and Find Full Text PDF[Spatiotemporal Patterns and Driving Forces Analysis of Ecological Carbon Sink from 2001 to 2022 in Qinling-Daba Mountains,China].
Huan Jing Ke Xue
January 2025
Shaanxi Key Laboratory of Earth Surface System and Environmental Carrying Capacity, College of Urban and Environmental Sciences, Northwest University, Xi'an 710127, China.
The Qinling-Daba Mountain area, an essential ecological conservation zone in China, occupies a pivotal position in the pursuit of carbon neutrality. Using diverse data sources, including temperature, precipitation, solar radiation, and the Normalized Difference Vegetation Index, we refined the CASA model by replacing model indicators. This enhanced model simulated the net primary productivity of vegetation in the Qinling-Daba Mountain area from 2001 to 2022.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!