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Impact of board-certified intensive care training facilities on choice of adjunctive therapies and prognosis of severe respiratory failure: a nationwide cohort study.
J Intensive Care
December 2024
Department of Health Data Science, Graduate School of Data Science, Yokohama City University, 22-2 Seto, Yokohama, Kanazawa, 236-0027, Japan.
Background: Patients with severe respiratory failure have high mortality and need various interventions. However, the impact of intensivists on treatment choices, patient outcomes, and optimal intensivist staffing patterns is unknown. In this study, we aimed to evaluate treatments and clinical outcomes for patients at board-certified intensive care training facilities compared with those at non-certified facilities.
View Article and Find Full Text PDFRole of sugammadex in the treatment of anaphylaxis due to rocuronium in children: Extrapolation from adult and animal reports.
Paediatr Anaesth
June 2022
Department of Anesthesiology & Pain Medicine, Nationwide Children's Hospital, The Ohio State University College of Medicine, Columbus, Ohio, USA.
Allergic reactions are generalized hypersensitivity processes triggered by different antigenic stimuli, resulting in the end effect of mast cell degranulation and adverse physiologic effects. During the perioperative period, the most commonly identified agents include antibiotics, neuromuscular blocking agents (rocuronium and succinylcholine), chlorhexidine, and iodinated dyes for radiologic imaging. Sugammadex is a novel agent for the reversal of neuromuscular blockade achieved with rocuronium or vecuronium.
View Article and Find Full Text PDFPrehospital Airway Management in Iraq and Afghanistan: A Descriptive Analysis.
South Med J
December 2018
From the US Army Institute of Surgical Research, Joint Base San Antonio-Fort Sam Houston, Texas, the 59th Medical Wing, Joint Base San Antonio-Lackland Air Force Base, Texas, the San Antonio Military Medical Center, Joint Base San Antonio-Fort Sam Houston, Texas, the Madigan Army Medical Center, Joint Base Lewis McChord, Washington, and the Army Medical Department Center and School Health Readiness Center of Excellence, Joint Base San Antonio-Fort Sam Houston, Texas.
Objectives: Airway failures are the second leading cause of potentially preventable death on the battlefield. Improvements in airway management depend on identifying current challenges. We sought to build on previously reported data on prehospital, combat airway management.
View Article and Find Full Text PDFInvestigation of intraoperative dosing patterns of neuromuscular blocking agents.
J Clin Monit Comput
June 2019
Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Boston, MA, 02115, USA.
There is a growing body of literature documenting the use of deep neuromuscular block (NMB) during surgery. Traditional definitions of depth of NMB rely on train-of-four assessment, which can be less reliable in retrospective studies. The goal of our study was to investigate the real-world practice pattern of dosing of neuromuscular blocking agents (NMBA), utilizing the amount of NMBA used during the course of a case, adjusted for patient weight and case duration, as a surrogate measure of depth of NMB.
View Article and Find Full Text PDFDexmedetomidine anesthesia enhances spike generation during intra-operative electrocorticography: A promising adjunct for epilepsy surgery.
Epilepsy Res
January 2015
Department of Neurology, National Institute of Mental Health and Neurosciences, Bangalore, Karnataka, India.
Background: Anesthetic-induced suppression of cortical electrical activity is a major concern during epilepsy surgery. Dexmedetomidine (Dex) has been recently evaluated in a few small series for its effect on the electrocorticographic spikes intra-operatively.
Methods: In this prospective study, electrocorticogram (ECoG) was monitored during dexmedetomidine infusion in 34 patients (M:F=23:11, age=29.
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