The present study shows the results of visualization experiments of the jet formation through a dynamic model of the human vocal folds. The model consists of two counter-rotating, 3D-shaped driven cams covered with a stretched silicone membrane. The 3D contours of the cams are a result of an optimized mapping of observed characteristic clinical vocal fold motions. The experiments are performed by using cams which produce the convex, triangular, rectangular, and concave or sand-glass regular glottis closure types. Two irregular cases are investigated: one of the convex cams is statically closed or opened. These cases cause an oscillating jet which attaches to the ventricular folds and appears to change the part of the aero-acoustic sound spectrum induced by vortices.
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http://dx.doi.org/10.3109/14015431003667652 | DOI Listing |
Mol Ther
January 2025
Department of Surgery, University of California San Diego, La Jolla, CA, 92093, United States; Department of Dermatology, University of California San Diego, La Jolla, CA, 92093, United States. Electronic address:
Small extracellular vesicles (sEVs) mediate intercellular signaling to coordinate proliferation of cell types that promote re-epithelialization of skin following injury. Cyclin-dependent kinase 1 (CDK1) drives cell division and is a key regulator of entry to cell cycle. To understand the potential of sEV-mediated delivery of CDK1 to reverse impaired wound healing, we generated CDK1-loaded sEVs (CDK1-sEVs) and evaluated their ability to mediate cell proliferation, re-epithelialization and downstream signaling responses in the wound bed.
View Article and Find Full Text PDFLife Sci Space Res (Amst)
February 2025
China Astronaut Research and Training center, Beijing 100094, PR China.
In order to explore the management and treatment methods of solid waste in the Controlled Ecological Life Support System (CELSS) of future lunar bases, during the 4-crew 180-day integrated experiment, the Solid Waste Management and Treatment System (SWMTS) was built, in which the treatment of recyclable solid waste such as inedible plant parts and human excrement was completed through a combination of biological aerobic composting and high-temperature oxidation. Basic data on the types and amounts of solid waste generated during the 4-crew 180-day experiment mission were obtained. There were six types of solid wastes, including the work support wastes, the household support wastes, the plant cultivation wastes, the plant-based wastes, and crew feces.
View Article and Find Full Text PDFCureus
December 2024
Medicine, Yangtze University, Jingzhou, CHN.
This study aimed to assess the results of reconstructive surgery with vacuum-assisted closure (VAC) therapy in patients with complex wounds. The sample included 60 patients with a mean age of 53.03 years.
View Article and Find Full Text PDFOper Neurosurg (Hagerstown)
July 2024
Department of Neurosurgery, Medical Center - University of Freiburg, Freiburg, Germany.
Background And Objective: A safe working trajectory is mandatory for spinal pathologies, especially in the midline, anterior to the spinal cord. For thoracic cerebrospinal fluid (CSF) leaks, we developed a minimally invasive keyhole fenestration. This study investigates the necessary bone removal for sufficient exposure of different leak types particularly regarding weight-bearing structures.
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