Background: Although the prevalence of strabismus is 2% to 5% in European-based and African-American populations, little is known about the prevalence of strabismus in Native-American populations. We report the prevalence of strabismus in children who are members of a Native-American tribe with a high prevalence of astigmatism.
Methods: Subjects were 594 children enrolled in Head Start and 315 children enrolled in kindergarten or first grade (K/1) in schools on the Tohono O'odham Reservation. Distance and near cover tests were performed on each child by an ophthalmologist or optometrist, and cycloplegic refraction was obtained.
Results: Strabismus was detected in 9 Head Start children (1.5%) and 3 K/1 children (1.0%). Ratio of esotropia to exotropia was 1:3 in Head Start and 1:2 in K/1. Anisometropia >or=1.00 diopter (D) spherical equivalent was present in 2 children with strabismus, and anisometropia >or=1.00 D cylinder was present in 4 with strabismus.
Conclusion: The prevalence of strabismus in Tohono O'odham children is at the low end of the prevalence range reported in studies of European-based and African-American populations.
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http://dx.doi.org/10.1016/j.optm.2009.10.010 | DOI Listing |
BMJ Open Ophthalmol
December 2024
Ophthalmology, Royal Hospital for Children, Glasgow, UK.
Background: Very premature infants screened for retinopathy of prematurity (ROP) that do not develop ROP still experience serious visual developmental challenges, and while it is recommended that all children in the UK are offered preschool visual screening, we aimed to explore whether this vulnerable group requires dedicated follow-up.
Methods: We performed a real-world retrospective observational cohort study of children previously screened for ROP in NHS Greater Glasgow and Clyde (Scotland) between 2013 and 2015. We excluded those with any severity of ROP identified during screening.
Sci Rep
December 2024
Department of Biology, School of Medicine, University of Zagreb, Salata 3, 10000, Zagreb, Croatia.
Retinoblastoma, a rare childhood eye cancer, has hereditary and non-hereditary forms. While TNM classification helps in prognosis, understanding molecular mechanisms is vital for the clinical behavior of retinoblastoma prediction. Our study aimed to analyze the expression levels of key Wnt pathway proteins, GSK3β, LEF1, β-catenin, and DVL1, and associate them to non-phosphorylated active form (pRb) and the phosphorylated inactive form (ppRb) and N-myc expression, in retinoblastoma cells and healthy retinal cells, in order to elucidate their roles in retinoblastoma and identify potential targets that could help to improve diagnostic and therapy.
View Article and Find Full Text PDFOphthalmic Plast Reconstr Surg
October 2024
Division of Ophthalmology, Children's Hospital of Philadelphia.
Background: Punctal agenesis (PA) is a rare congenital anomaly that can occur in isolation or as part of an underlying syndrome. The benefit of genetic assessment in individuals with PA and clinical features that should prompt molecular workup has not been systematically studied. The aim of this study was to identify ocular and extraocular features associated with PA and determine its association with an underlying syndrome.
View Article and Find Full Text PDFBMC Ophthalmol
December 2024
School of Rehabilitation, Tehran University of Medical Sciences, Tehran, Iran.
Background: acquired exotropia mostly manifests as an intermittent form, and very few cases show constant exotrpia. However, the differences in the clinical features of the constant and intermittent exotropia patients has not been clear yet.
Methods: We retrospectively evaluated 6159 patients with exotropia from 2012 to 2022 in Farabi Eye Hospital, Tehran, Iran.
Health Sci Rep
December 2024
Department of Surgery College of Medicine, University of Baghdad Baghdad Iraq.
Background And Aims: Refractive errors and intermittent exotropia are prevalent conditions in pediatric populations, impacting visual development and quality of life. Despite the co-occurrence of conditions such as myopia, hypermetropia, and astigmatism with strabismus, comprehensive analyses of their coexistence are limited. This study aims to investigate the prevalence and characteristics of refractive error among children with intermittent exotropia and find the correlation between the angle of deviation for far and near with factors like mean spherical equivalent and age.
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