AI Article Synopsis
- The study aimed to explore the relationship between depression and cognitive function in Hepatitis C and chronic liver disease patients awaiting liver transplants, considering the influence of alcohol use and MELD scores.
- A total of 40 patients underwent neuropsychological testing and depression assessments at a medical center in São Paulo.
- Results indicated significant cognitive differences in patients based on their MELD scores, particularly in areas like estimated IQ and memory, suggesting the need for further research to better understand and support these patients.
Article Abstract
Objective: To investigate the links between depression and cognitive functioning in patients with Hepatitis C and other chronic liver diseases with and without the use of alcohol on the waiting list for liver transplantation and their associations with the MELD classification.
Method: 40 patients were evaluated on a waiting list for liver transplant by a battery of neuropsychological tests, depression scales and interview at the Liver Transplant Service, of the Hospital das Clínicas University of São Paulo Medical School.
Results: After splitting the sample according to the education, the results showed statistical significance in the comparisons between groups of MELD > 15 and <15 in the following functions: estimated IQ, visual-spatial delayed recall and recognition as part of episodic memory and short term memory.
Conclusion: These findings, usually found in hepatic encephalopathy, corroborated with the literature and emphasized the need to investigate in more detail the cognitive functions of these patients in order to facilitate the adoption of different conducts.
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| http://dx.doi.org/10.1590/s0004-282x2010000100014 | DOI Listing |
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