In modern endoscopy, wide field of view and full color are considered necessary for navigating inside the body, inspecting tissue for disease and guiding interventions such as biopsy or surgery. Current flexible endoscope technologies suffer from reduced resolution when device diameter shrinks. Endoscopic procedures today, using coherent fiber-bundle technology on the scale of 1 mm, are performed with such poor image quality that the clinician's vision meets the criteria for legal blindness. Here, we review a new and versatile scanning fiber-imaging technology and describe its implementation for ultrathin and flexible endoscopy. This scanning fiber endoscope (SFE) or catheterscope enables high-quality, laser-based, video imaging for ultrathin clinical applications, while also providing new options for in vivo biological research of subsurface tissue and high resolution fluorescence imaging.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3163080PMC
http://dx.doi.org/10.1002/jbio.200900087DOI Listing

Publication Analysis

Top Keywords

scanning fiber
8
fiber endoscopy
4
endoscopy highly
4
highly flexible
4
flexible catheterscopes
4
catheterscopes wide-field
4
wide-field full-color
4
full-color imaging
4
imaging modern
4
modern endoscopy
4

Similar Publications

NetSDR: Drug repurposing for cancers based on subtype-specific network modularization and perturbation analysis.

Biochim Biophys Acta Mol Basis Dis

January 2025

MOE Key Laboratory of Geriatric Diseases and Immunology, Suzhou Key Laboratory of Pathogen Bioscience and Anti-infective Medicine, Department of Bioinformatics and Computational Biology, School of Life Sciences, Suzhou Medical College of Soochow University, Suzhou 215123, China; Jiangsu Province Engineering Research Center of Precision Diagnostics and Therapeutics Development, Soochow University, Suzhou 215123, China; Key Laboratory of Alkene-carbon Fibres-based Technology & Application for Detection of Major Infectious Diseases, Soochow University, Suzhou 215123, China; Jiangsu Key Laboratory of Infection and Immunity, Soochow University, Suzhou 215123, China. Electronic address:

Cancer, a heterogeneous disease, presents significant challenges for drug development due to its complex etiology. Drug repurposing, particularly through network medicine approaches, offers a promising avenue for cancer treatment by analyzing how drugs influence cellular networks on a systemic scale. The advent of large-scale proteomics data provides new opportunities to elucidate regulatory mechanisms specific to cancer subtypes.

View Article and Find Full Text PDF

Polycyclic aromatic hydrocarbons (PAHs) are carcinogenic compounds resulting from incomplete burning of organic materials. This work describes the successful layer-by-layer fabrication of a novel zinc oxide nanocomposite made of zinc oxide nanoparticles, aniline, sodium dodecyl sulfate, and modified multi-walled carbon nanotubes on a stainless steel wire by electrodeposition. The coating and extraction conditions were screened, optimized, and validated using factorial design and central composite design, respectively.

View Article and Find Full Text PDF

Acoustic, Mechanical, and Thermal Characterization of Polyvinyl Acetate (PVA)-Based Wood Composites Reinforced with Beech and Oak Wood Fibers.

Polymers (Basel)

January 2025

Research Laboratory for Sustainable Development and Health, Department of Applied Physics, Faculty of Sciences and Technics, Cadi Ayyad University, Marrakesh 40000, Morocco.

Considering the growing need for developing ecological materials, this study investigates the acoustic, mechanical, and thermal properties of wood composites reinforced with beech or oak wood fibres. Scanning electron microscopy (SEM) revealed a complex network of interconnected pores within the composite materials, with varying pore sizes contributing to the material's overall properties. Acoustic characterization was conducted using a two-microphone impedance tube.

View Article and Find Full Text PDF

The present work constitutes the initial experimental effort to characterise the dynamic tensile performance of basalt fibre grids employed in TRM systems. The tensile behaviour of a bi-directional basalt fibre grid was explored using a high-speed servo-hydraulic testing machine with specialised grips. Deformation and failure modes were captured using a high-speed camera.

View Article and Find Full Text PDF

Histology Assessment of Chitosan-Polyvinyl Alcohol Scaffolds Incorporated with CaO Nanoparticles.

Molecules

January 2025

Grupo Biomateriales Dentales, Escuela de Odontología, Universidad del Valle, Calle 4B # 36-00, Cali 760001, Colombia.

Scaffolds for regenerative therapy can be made from natural or synthetic polymers, each offering distinct benefits. Natural biopolymers like chitosan (CS) are biocompatible and biodegradable, supporting cell interactions, but lack mechanical strength. Synthetic polymers like polyvinyl alcohol (PVA) provide superior mechanical strength and cost efficiency but are not biodegradable or supportive of cell adhesion.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!