A new flavone C-glycoside, isovitexin 6''-O-E-p-coumarate (1) and two known flavonoid glycosides--quercetin 3-O-beta-D-glucuronopyranoside (2) and isoorientin (3)--were isolated from an ethanol extract of aerial parts of Clematis rehderiana. Their structures were determined by spectroscopic methods. The antioxidant effects of the two flavone C-glycosides were evaluated by both the MTT and DPPH assays. Compound 1 showed potent activities against H2O2-induced impairment in PC12 cells within the concentration range tested, whereas compound 3 scavenged DPPH radical strongly, with an IC50 value of 13.5 microM.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6263201 | PMC |
| http://dx.doi.org/10.3390/molecules15020672 | DOI Listing |
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