AI Article Synopsis
- Six new derivatives of selaginellin, including three previously unknown ones (selaginellins D-F), were extracted from the Selaginella pulvinata plant.
- The structures of these compounds were identified through detailed physical and chemical analysis.
- Compounds 1 and 4 showed antifungal effects against Candida albicans, while compounds 4-6 were notably effective against the bacteria Staphylococcus aureus.
Article Abstract
Six selaginellin derivatives, including three new analogues selaginellins D-F (1-3), were isolated from the EtOAc extract of the whole plant of Selaginella pulvinata (Hook. et Grev.) Maxim. Their structures were determined on the basis of extensive physical and chemical evidence. Compounds 1 and 4 demonstrated antifungal activities against Candida albicans; compounds 4-6 exhibited significant antibacterial activity against Staphylococcus aureus.
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| http://dx.doi.org/10.1016/j.bmcl.2010.03.016 | DOI Listing |
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