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A Modular Engineered DNA Nanodevice for Precise Profiling of Telomerase RNA Location and Activity.
Adv Sci (Weinh)
December 2024
State Key Laboratory of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing, 210023, P. R. China.
Increased telomerase activity has been considered as a conspicuous sign of human cancers. The catalytic cores of telomerase involve a reverse transcriptase and the human telomerase RNA (hTR). However, current detection of telomerase is largely limited to its activity at the tissue and single-cell levels.
View Article and Find Full Text PDFArtificial neural networks and machine learning in anesthesia and perioperative medicine: Reflections on the 2024 Nobel prize in physics.
J Clin Anesth
December 2024
Graduate School of Anhui Medical University, Anhui 236000, China. Electronic address:
Commemorating the 1924 Nobel Prize Awarded to Willem Einthoven: A Century of Progress in Electrocardiography and Arrhythmia Research.
Europace
December 2024
Translational Cardiology, Department of Cardiology and Department of Physiology, Inselspital University Hospital Bern, University of Bern, 3012 Bern, Switzerland.
Beyond the Nobel prizes: towards new synergies between Computational Neuroscience and Artificial Intelligence.
Biol Cybern
December 2024
Physics Department, Humboldt University Berlin, Newtonstr. 15, 12489, Berlin, Germany.
Evolution in electrophysiology 100 years after Einthoven: translational and computational innovations in rhythm control of atrial fibrillation.
Europace
December 2024
Gottfried Schatz Research Center, Division of Medical Physics and Biophysics, Medical University of Graz, Graz, Austria.
In 1924, the Dutch physiologist Willem Einthoven received the Nobel Prize in Physiology or Medicine for his discovery of the mechanism of the electrocardiogram (ECG). Anno 2024, the ECG is commonly used as a diagnostic tool in cardiology. In the paper 'Le Télécardiogramme', Einthoven described the first recording of the now most common cardiac arrhythmia: atrial fibrillation (AF).
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