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Brazil-Portugal Comparison: Education, Health and Social Development in light of the Sustainable Development Goals.
Rev Bras Enferm
January 2025
Universidade Federal de Santa Catarina. Florianópolis, Santa Catarina, Brazil.
Objective: to comparatively analyze the health, education and social development systems of Brazil and Portugal, their relationship with the Sustainable Development Goals and the Organization for Economic Cooperation and Development averages.
Method: exploratory and descriptive qualitative research, through documentary analysis. The indicators address health, education and social development, considering life expectancy, mortality, prevalence of chronic diseases, literacy, educational performance and poverty rates.
Rural Culture and Diabetes Self-Management Beliefs, Behaviors and Health Outcomes.
Nurs Res
January 2025
Bassett Research Institute, Bassett Medical Center, Cooperstown, NY.
Background: Rural populations in the United States face a diabetes mortality penalty. Self-management is a core component of treatment for type 2 diabetes, but there is low uptake of self-management education and support interventions in rural areas. Rural structural barriers to diabetes self-management have been described, yet the role of rural culture has not been extensively explored.
View Article and Find Full Text PDFGuidelines for Gene and Genome Assembly Nomenclature.
Genetics
January 2025
EMBL-EBI - Non-Vertebrate Genomics Team, European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Cambridge CB10 1SD, UK.
The rapid increase in the number of reference-quality genome assemblies presents significant new opportunities for genomic research. However, the absence of standardized naming conventions for genome assemblies and annotations across datasets creates substantial challenges. Inconsistent naming hinders the identification of correct assemblies, complicates the integration of bioinformatics pipelines, and makes it difficult to link assemblies across multiple resources.
View Article and Find Full Text PDFInterventions to Reduce Mental Health Stigma in Young People: A Systematic Review and Meta-Analysis.
JAMA Netw Open
January 2025
Millennium Nucleus to Improve the Mental Health of Adolescents and Youths (IMHAY), Santiago, Chile.
Importance: Mental health stigma is a considerable barrier to help-seeking among young people.
Objective: To systematically review and meta-analyze randomized clinical trials (RCTs) of interventions aimed at reducing mental health stigma in young people.
Data Sources: Comprehensive searches were conducted in the CENTRAL, CINAHL, Embase, PubMed, and PsycINFO databases from inception to February 27, 2024.
Elucidating stearoyl metabolism and NCOA4-mediated ferroptosis in gastric cancer liver metastasis through multi-omics single-cell integrative mendelian analysis: advancing personalized immunotherapy strategies.
Discov Oncol
January 2025
Western Institute of Digital-Intelligent Medicine, 401329, Chongqing, China.
Background: The metabolism of stearoyl-GPE plays a key role in the liver metastasis of gastric cancer. This investigation delves into the mechanisms underlying the intricate tumor microenvironment (TME) heterogeneity triggered by stearoyl metabolism in gastric cancer with liver metastasis (LMGC), offering novel perspectives for LMGC.
Objective: Utilizing Mendelian randomization, we determined that stearoyl metabolism significantly contributes to the progression of gastric cancer (GC).
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