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J Hist Med Allied Sci
January 2025
University of Wisconsin-Madison, Wisconsin, USA.
This paper provides a case study of one medical experiment conducted in 1915 by the United States Public Health Service in collaboration with the Mississippi State Penitentiary. The experiment was non-therapeutic and its objective was to induce pellagra (a vitamin deficiency disease) in twelve healthy White male prisoners to confirm its etiology. Extant archival records produced by the convict participants, state politicians, and health researchers underscore that the men selected for the pellagra experiment were unique among incarcerated people in Mississippi at the time: they were White, wealthy, and politically well-connected.
View Article and Find Full Text PDFCureus
October 2024
Medicine, Johns Hopkins University School of Medicine, Baltimore, USA.
Pellagra, a rare disorder caused by niacin deficiency, manifests as 4Ds: dermatitis, diarrhea, dementia, and, if left untreated, death. Though it was thought to be eradicated from the United States after fortification with niacin, there have been concerns about its reemergence in specific high-risk populations such as chronic alcoholism, malabsorption, and anorexia nervosa. Here we present a patient with altered mental status who subsequently developed diarrhea during the course of hospitalization.
View Article and Find Full Text PDFJ R Coll Physicians Edinb
December 2024
Department of Dermatology & Venereology, Maulana Azad Medical College, New Delhi, Delhi, India.
Rev Colomb Psiquiatr (Engl Ed)
November 2024
Instituto de Neuropsiquiatría y Adicciones (INAD), Centros Asistenciales Dr. Emili Mira i López (CAEMIL-Recinto Torribera), Parc de Salut Mar, Santa Coloma de Gramenet, Barcelona, Spain.
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