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Endoscopic capsule placement improves the completion rate of small-bowel capsule endoscopy and increases diagnostic yield. | LitMetric
Background : The methods for increasing the rate of complete small-bowel examinations by capsule endoscopy (CE) demonstrate conflicting results, and it is unknown whether improving the completion rate of CE transit is correlated with improvement in diagnostic yield.Objective : The aim of this study was to determine whether a higher rate of complete small-bowel examinations results in a higher diagnostic yield of CE.Design : Case-control comparison.Setting : Tertiary care university hospital.Patients : A total of 273 patients underwent conventional CE (group A), and 261 patients underwent real-time CE (group B). Furthermore, the patients in groups A and B were divided into 2 subgroups by pyloric transit time (A1, A2 and B1, B2, respectively).Interventions : After swallowing the capsule, each patient was monitored with a real-time viewer in group B, and the patients underwent endoscopic placement if the capsule was delayed in the esophagus or stomach.Main Outcome Measurements : Pyloric transit time, small-bowel transit time, the rate of complete small-bowel examinations, and the diagnostic yield.Results : The rate of complete small-bowel examinations was significantly higher in group B than in group A (87.4% vs 78.0%, respectively; P = .004). The diagnostic yield was significantly higher in group B2 than in group A2 (60.0% vs 41.7%, respectively; P = .019).Limitations : Nonrandomized study.Conclusions : Endoscopic placement improves the rate of complete small-bowel examinations, resulting in a higher diagnostic yield of CE.
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