A novel photocatalyst - ILUMIO (platinum-loaded tungsten oxide) - was evaluated for its anti-influenza virus activity with the avian isolate A/northern pintail/Miyagi/1472/08 (H1N1). Under a fluorescent lamp of 1000lx in the absence of ultraviolet light, the virus was inactivated to below the detection limit i.e. >5.3log inactivation within 2h. This photocatalyst can be used for coating walls, tables, and other surfaces to decrease virus infectivity associated with surfaces. This would be desirable to reduce transmission of infection due to indirect contact, because self-inoculation of the nasal mucosa by contaminated hands is a major transmission mode of influenza viruses from human to human, alongside with transmissions via aerosols and droplets.
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http://dx.doi.org/10.1016/j.virusres.2010.03.006 | DOI Listing |
Vaccines (Basel)
December 2024
Laboratory of Avian Diseases, College of Veterinary Medicine, Seoul National University, Seoul 08826, Republic of Korea.
Highly pathogenic (HP) H5Nx and low-pathogenicity (LP) H9N2 avian influenza viruses (AIVs) pose global threats to the poultry industry and public health, highlighting the critical need for a dual-protective vaccine. In this study, we generated a model PR8-derived recombinant H5N2 vaccine strain with hemagglutinin (HA) and neuraminidase (NA) genes from clade 2.3.
View Article and Find Full Text PDFVet World
November 2024
Department of Animal Biotechnology, Mahanakorn University of Technology, Bangkok, Thailand.
Background And Aim: Potassium peroxymonosulfate (PPMS) is a broad-spectrum disinfectant that oxidizes viral protein capsids. The effectiveness of PPMS in killing viruses depends on several factors, including its concentration, contact time, and present of organic materials. This study evaluated the efficacy of PPMS in an aqueous phase.
View Article and Find Full Text PDFInfect Genet Evol
January 2025
Avian Disease Division, Animal and Plant Quarantine Agency, Gimcheon 39660, Gyeongsangbuk-do, Republic of Korea. Electronic address:
Infectious bronchitis (IB), caused by the infectious bronchitis virus (IBV), is a highly contagious chicken disease, causing economic losses worldwide. New IBV strains and variants continue to emerge despite using inactivated and live-attenuated vaccines to prevent or control IB. In this study, the S1 genes of 46 IBV strains, isolated from commercial chicken flocks between 2003 and 2024 in Korea were sequenced and genetically characterized.
View Article and Find Full Text PDFVet Med Sci
January 2025
Department of Animal Nutrition and Nutritional Disease, Faculty of Veterinary Medicine, Burdur Mehmet Akif Ersoy University, Burdur, Turkey.
Photodynamic inactivation (PDI) is a new and promising strategy for eliminating foodborne pathogenic bacteria in food preservation, reducing associated health risks for consumers. This study aimed to develop an innovative PDI-based system to inactivate Salmonella Enteritidis PT4 on eggshells. The system includes 405 nm light-emitting diodes (LEDs) and the application of curcumin or carvacrol as photosensitizers.
View Article and Find Full Text PDFVet Immunol Immunopathol
January 2025
Department of Veterinary and Animal Sciences, University of Copenhagen, Dyrlægevej 88, Frederiksberg C 1870, Denmark.
Newcastle disease (ND) is a notifiable avian disease responsible for several panzootics, which has resulted in the establishment of mandatory vaccination programs against the virus in several countries including Denmark. This study compared the immune response elicited in layers by the standard vaccination program for ND of a Danish commercial egg production facility with a simplified version of the vaccination program. A commercial flock of layers was followed for 77 weeks from hatching to culling.
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