Objective: The aim of the study was to investigate treatment outcome of mandibular advancement devices (MADs) for positional and nonpositional obstructive sleep apnea (OSA).
Study Design: Forty-two positional (supine apnea-hypopnea index [AHI] > or = 2 times lateral AHI) and 30 nonpositional (supine AHI < 2 times lateral AHI) OSA patients performed 2-nights of sleep study before and after insertion of MADs.
Results: The decreases in apnea severity based on a reduction in the overall and supine AHI values after MADs therapy were significantly greater for the positional OSA than nonpositional OSA group. A multiple linear regression analysis showed that decrease in overall AHI was significantly associated with being in the positional group (standardized coefficient = 0.505). Age, body mass index, gender, and time in supine position during sleep did not show significant associations with decrease in overall AHI after MAD therapy.
Conclusion: Our data suggest that MADs are more effective in positional OSA than nonpositional OSA patients.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4190179 | PMC |
| http://dx.doi.org/10.1016/j.tripleo.2009.11.031 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Evaluating Positional Obstructive Sleep Apnea in Children: Prevalence, Characteristics, and Risk Factors.
Nat Sci Sleep
October 2024
Department of Otolaryngology-Head and Neck Surgery, Capital Institute of Pediatrics, Beijing, People's Republic of China.
Article Synopsis
- The study examines the prevalence and characteristics of positional obstructive sleep apnea (POSA) in children with obstructive sleep apnea (OSA), analyzing 1,236 pediatric patients.
- After filtering, 153 POSA and 306 non-positional OSA (NPOSA) patients were compared, revealing that POSA had a prevalence of 12.8%.
- Results indicated that POSA patients had lower overall apnea-hypopnea indices (AHI), shorter total sleep time, and spent more time in non-supine sleep positions, suggesting that changes in sleep position could help reduce apnea occurrences in children.
Polysomnographic phenotypes: predictors of treatment response in Obstructive Sleep Apnea with Mandibular Advancement devices.
Eur Arch Otorhinolaryngol
September 2024
Senior Lecturer, Department of Stomatology, Faculty of Medicine and Dentistry, University of Valencia, Valencia, Spain.
Article Synopsis
- This study investigates how different characteristics of patients with obstructive sleep apnea (OSA) can predict their response to mandibular advancement devices (MAD) and aims to create a model for treatment efficacy.
- It analyzed 112 patients over six years, categorizing OSA into different phenotypes, with findings indicating that positional-OSA patients had a significantly higher response rate to MAD compared to non-positional patients.
- The results suggest that specific phenotypes, particularly REM-OSA, are less responsive to MAD treatment, highlighting key metrics like hypoxic burden and T90% that are useful in predicting treatment success in OSA patients.
Long-term mortality risk in obstructive sleep apnea: the critical role of oxygen desaturation index.
Sleep Breath
December 2024
Faculty of Medicine, Department of Pulmonology, Istinye University, Istanbul, Turkey.
Background: Mortality predictors in obstructive sleep apnea (OSA) patients yet to be comprehensively understood, especially within large cohorts undergoing long-term follow-up. We aimed to determine the independent predictors of mortality in OSA patients.
Methods: In our retrospective cohort study, 3,541 patients were included and survival data was obtained from electronic medical records.
[Analysis of the difference of therapeutic effect and predictive factors between postural and non-postural OSA after modified uvulopalatopharyngoplasty].
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
August 2024
To analyze the factors influencing the outcome of uvulopalatopharyngoplasty in positional obstructive sleep apnea（POSA） and non-positional OSA（NPOSA） patients, and to explore the differences between the two groups. The data of 101 patients with obstructive sleep apnea who received treatment from November 2020 to November 2023 were retrospectively analyzed. Among them, 45 positional patients（POSA group） and 56 non-positional patients（NPOSA group）, who underwent overnight polysomnography were included.
View Article and Find Full Text PDFSupine or non-supine sleep apnea events: which can be treated better with Barbed Pharyngoplasty?
Sleep Breath
October 2024
School of Medicine, Università Campus Bio-Medico di Roma, Rome, Italy.
Purpose: Among the treatment options for Obstructive Sleep Apnea (OSA), intrapharyngeal surgery has undergone significant changes and received solid scientific support. However, it is crucial to identify the best candidate. This study aims to present the results of the modified Alianza technique in our clinic to show the differences in the impact of surgery on supine and non-supine apnea levels in moderate-severe OSA patients.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!