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Seroepidemiology of human leptospirosis in the Dominican Republic: A multistage cluster survey, 2021.
PLoS Negl Trop Dis
December 2024
University of Queensland Centre of Clinical Research (UQCCR), University of Queensland, Brisbane, Australia.
Little is known about the epidemiology of leptospirosis in the Dominican Republic, the second most populous country in the Caribbean. We report on findings from a multi-stage household survey across two regions in the country that reveals a previously under-estimated burden of human Leptospira infection. Our findings, based on the reference-standard microscopic agglutination test, indicate a complex picture of serogroup diversity, spatial heterogeneity in infection and risk, and a marked discrepancy between reported cases and serologically estimated infections.
View Article and Find Full Text PDFA Rare Case of Weil's Disease Presenting With Severe Hyperbilirubinemia and Acute Kidney Injury: A Diagnostic Challenge in Urban England.
Cureus
November 2024
Internal Medicine, Northumbria Healthcare NHS Trust, Newcastle-Upon-Tyne, GBR.
We present a rare and challenging case of Weil's disease in a patient who was admitted to the Critical Care Unit with a clinical suspicion of the condition. The patient showed a prompt response to treatment before laboratory confirmation was obtained. Leptospirosis, a zoonotic disease, is most commonly found in tropical and temperate regions.
View Article and Find Full Text PDFCLINICAL MANIFESTATION AND EPIDEMIOLOGICAL PECULIARITIES OF LEPTOSPIROSIS AT THE MODERN STAGE IN GEORGIA.
Georgian Med News
September 2024
1Tbilisi State Medical University, The First University Clinic, Georgia.
Introduction: Leptospirosis is considered one of the most common zoonotic infections in the world and is characterized by distribution in countries of subtropical and tropical zones. In Georgia A sharp increase in the frequency of leptospirosis began in 2011, and the morbidity rate increased to 16.3.
View Article and Find Full Text PDFAn Interesting Case of Weil's Disease with Diagnostic Challenges.
Cureus
October 2024
Pulmonary Medicine, One Brooklyn Health- Interfaith Medical Center, New York City, USA.
Article Synopsis
- Weil's disease is a serious form of leptospirosis that can lead to high mortality, with symptoms ranging from mild febrile illness to severe multiorgan failure.
- A case study of a young immigrant showed symptoms like abdominal pain, vomiting, and body aches, along with issues like elevated bilirubin levels and acute kidney injury.
- Despite initial tests being negative, the patient's symptoms and travel history indicated leptospirosis, confirmed by a positive IgM test, highlighting the importance of considering rare infections in diagnosis.
Leptospirosis and melioidosis coinfection presenting as acute respiratory distress syndrome and osteomyelitis: Case report and systematic review.
J Infect Dev Ctries
August 2024
Department of Pulmonary Medicine & Critical Care, All India Institute of Medical Sciences, Bhubaneswar, India.
Introduction: Leptospirosis and melioidosis are common in tropical and temperate climates and can be acquired by exposure to contaminated water and soil. However, concomitant leptospirosis and melioidosis infection is rarely described in the literature. We report a case of leptospirosis-melioidosis coinfection and systematically review the literature.
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