Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
The effect of Lewy body (co-)pathology on the clinical and imaging phenotype of amnestic patients.
Brain
January 2025
Reina Sofia Alzheimer Centre, CIEN Foundation, ISCIII, Madrid, Spain.
Lewy body (LB) pathology is present as a co-pathology in approximately 50% of Alzheimer's disease (AD) dementia patients and may even represent the main neuropathologic substrate in a subset of patients with amnestic impairments. However, the degree to which LB pathology affects the neurodegenerative course and clinical phenotype in amnestic patients is not well understood. Recently developed α-synuclein seed amplification assays (αSyn-SAAs) provide a unique opportunity for further investigating the complex interplay between AD and LB pathology in shaping heterogeneous regional neurodegeneration patterns and clinical trajectories among amnestic patients.
View Article and Find Full Text PDFRetraction Note: Letter to editor: Comment on, "Unveiling rupture risk and clinical outcomes in midline aneurysms: a matched cohort analysis investigating the impact of localization within the anterior or posterior circulation".
Neurosurg Rev
January 2025
Department of Cariology, Saveetha Institute of Medical and Technical Sciences (SIMATS), Saveetha Dental College and Hospitals, Saveetha University, Chennai, 600 077, India.
Imaging biomarkers of cortical neurodegeneration underlying cognitive impairment in Parkinson's disease.
Eur J Nucl Med Mol Imaging
January 2025
Reina Sofia Alzheimer Center, CIEN Foundation, ISCIII, Madrid, Spain.
Purpose: Imaging biomarkers bear great promise for improving the diagnosis and prognosis of cognitive impairment in Parkinson's disease (PD). We compared the ability of three commonly used neuroimaging modalities to detect cortical changes in PD patients with mild cognitive impairment (PD-MCI) and dementia (PDD).
Methods: 53 cognitively normal PD patients (PD-CN), 32 PD-MCI, and 35 PDD underwent concurrent structural MRI (sMRI), diffusion-weighted MRI (dMRI), and [F]FDG PET.
Peptide-Bound Aflibercept Eye Drops for Treatment of Neovascular Age-Related Macular Degeneration in Nonhuman Primates.
Adv Sci (Weinh)
January 2025
Department of Pharmaceutics, School of Pharmacy, Fudan University & Key Laboratory of Smart Drug Delivery (Fudan University), Ministry of Education, Shanghai, 201203, China.
The advent of biomacromolecules antagonizing vascular endothelial growth factor (VEGF) has revolutionized the treatment of neovascular age-related macular degeneration (nAMD). However, frequent intravitreal injections of these biomacromolecules impose an enormous burden on patients and create a massive workload for healthcare providers. This causes patients to abandon therapy, ultimately leading to progressive and irreversible vision loss.
View Article and Find Full Text PDFComparison of the Histological Structure of an Anterior as well as a Posterior Biopsy From the Human Palate: A Comparative Study.
J Clin Periodontol
January 2025
Clinic of Reconstructive Dentistry, University of Zurich, Zurich, Switzerland.
Aim: To compare the histological structure of biopsies from the anterior and posterior regions of the human palate in order to gain insights into potential differences of soft tissue harvesting sites.
Methods: This comparative study involved 20 participants, from each of whom four samples from the palatal mucosa were collected. The biopsies were histologically processed and subsequently analysed.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!