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Age-period-cohort analysis of self-harm incidence rates by gender in Iran among individuals aged 10-39 years, 1990-2019.
Sci Rep
January 2025
Family Health and Population Growth Research Center, Health Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran.
This study investigates trends and patterns in self-harm incidence rates among individuals aged 10-39 years in Iran from 1990 to 2019. Using Age-Period-Cohort (APC) analysis, it aims to identify significant age, period, and cohort effects, and to highlight gender-specific trends for effective prevention strategies. Utilizing data from the Global Burden of Disease (GBD) study, we performed an APC analysis to assess trends in self-harm incidence rates by gender.
View Article and Find Full Text PDFExploring the impact of entrepreneurial orientation and market orientation on entrepreneurial performance in the context of environmental uncertainty.
Sci Rep
January 2025
Automotive Business School, Hubei University of Automotive Technology, Shiyan, 442000, Hubei, China.
In the current complex economic environment, entrepreneurial enterprises, as a crucial force in China's economic transformation, have vital survival and development strategies. This study is grounded in resource-based theory, integrating strategic management and contingency theories. It establishes a theoretical model based on the influence pathway of "entrepreneurial orientation-market orientation-entrepreneurial performance", incorporating environmental uncertainty as a moderating variable.
View Article and Find Full Text PDFSpecification of claustro-amygdalar and palaeocortical neurons and circuits.
Nature
January 2025
Department of Neuroscience, Yale School of Medicine, New Haven, CT, USA.
The ventrolateral pallial (VLp) excitatory neurons in the claustro-amygdalar complex and piriform cortex (PIR; which forms part of the palaeocortex) form reciprocal connections with the prefrontal cortex (PFC), integrating cognitive and sensory information that results in adaptive behaviours. Early-life disruptions in these circuits are linked to neuropsychiatric disorders, highlighting the importance of understanding their development. Here we reveal that the transcription factors SOX4, SOX11 and TFAP2D have a pivotal role in the development, identity and PFC connectivity of these excitatory neurons.
View Article and Find Full Text PDFApplication of three statistical approaches to explore effects of dietary intake of multiple persistent organic pollutants on ER-positive breast cancer risk in the French E3N cohort.
Sci Rep
January 2025
Inserm, Gustave Roussy, Centre for Research in Epidemiology and Population Health (CESP), "Exposome, Heredity, Cancer, and Health" Team, Université Paris-Saclay, UVSQ, 12 Avenue Paul Vaillant Couturier, 94805, Villejuif, France.
Persistent organic pollutants (POPs) are a group of organic chemical compounds. Contradictory results have emerged in epidemiological studies attempting to elucidate their relationship with breast cancer risk. This study explored the relationship between dietary exposures to multiple POPs and ER-positive breast cancer risk in the French E3N cohort study, using three different approaches to handle multicollinearity among exposures.
View Article and Find Full Text PDFStudy on the crack propagation morphology and initiation law of coal rock under the action of underwater electric pulse.
Sci Rep
January 2025
School of Resources and Civil Engineering, Northeastern University, Shenyang, 110819, China.
Based on the symmetric initiation mechanism of double-wing cracks in coal rock mass induced by high-pressure electro-recoil water pressure, fracturing experiments have been performed on coal rock mass under different water pressures and discharge conditions using high-voltage electric pulse hydraulic fracturing devices. Combined with CT scans, the crack spatial distribution inside the post-break coal rock mass was analyzed and found that the edge of the water injection hole is prone to produce double-wing cracks along the drilling hole diameter. ABAQUS is used to verify the physical test and extend the test conditions, the geometric parameter change, morphological expansion rule and crack initiation mechanism of double-wing crack in coal rock mass under different discharge conditions and ground stress conditions are studied.
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