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Pharmacologic blockade of nicotinic receptors in the suprachiasmatic nucleus increases ovarian atresia and inhibits follicular growth.
J Neuroendocrinol
September 2024
Physiology of Reproduction Laboratory, Biology of Reproduction Research Unit, Facultad de Estudios Superiores Zaragoza, Universidad Nacional Autónoma de México, Mexico City, Mexico.
Reproduction in all mammalian species depends on the growth and maturation of ovarian follicles, that is, folliculogenesis. Follicular development can culminate with the rupture of mature follicles and the consequent expulsion of their oocytes (ovulation) or in atresia, characterized by the arrest of development and eventual degeneration. These processes are regulated by different neuroendocrine signals arising at different hypothalamic nuclei, including the suprachiasmatic nucleus (SCN).
View Article and Find Full Text PDFA metabolomics approach for the evaluation of Ficus benghalensis female in vivo reproductive effects relative to its metabolite fingerprint as determined via UPLC-MS and GC-MS.
J Ethnopharmacol
March 2024
Department of Pharmacognosy, College of Pharmacy, Cairo University, Cairo, 11562, Egypt. Electronic address:
Ethnopharmacological Relevance: Ficus benghalensis, commonly known as Banyan Fig, is the national tree of India and its aerial roots are used traditionally to treat female reproductive disorders. However, despite this traditional use, no pharmacological evidence could be traced supporting this use. Additionally, no comprehensive metabolite profiling was reported for F.
View Article and Find Full Text PDFCanine Vaginal Cytology: A Revised Definition of Exfoliated Vaginal Cells.
Front Vet Sci
March 2022
Clinic for Animal Reproduction, Freie Universitaet Berlin, Berlin, Germany.
Vaginal cytology is an important examination method in the context of gynecological disorders and cycle staging in the bitch. While collection and preparation of samples are easy, the evaluation appears to be challenging. Inconsistent definitions of cell attributes such as size, cornification and the appearance of the nucleus have been published.
View Article and Find Full Text PDFThe Effect of BNR17 on Postmenopausal Symptoms in Ovariectomized Rats.
J Microbiol Biotechnol
September 2021
AceBiome Inc., Seoul 06164, Republic of Korea.
Clinical and preclinical studies have reported that BNR17, a probiotic bacterial strain isolated from human breast milk, reduces body weight and white adipose tissue volume. In order to further explore the actions of BNR17, we investigated the anti-menopausal effects of BNR17 in an ovariectomized (OVX) rat model. The serum alanine aminotransferase levels of the rats in the OVX-BNR17 group were lower than those of the rats in the OVX-vehicle only (OVX-Veh) group.
View Article and Find Full Text PDFPhytochemical analysis and antifertility potential of in female Wistar rats: A herbal approach towards contraception.
Chin Herb Med
July 2020
Department of Pharmacology, Poona College of Pharmacy, Bharati Vidyapeeth Deemed University, Pune 411041, India.
Objective: The objective of the present study was to evaluate the antifertility activity of ether (ErCD), chloroform (CeCD) and ethyl alcohol (EyCD) extracts of the whole plant of in female Wistar albino rats.
Methods: Acute oral toxicity and an antifertility study were performed in female Wistar rats with two dose levels (200 and 400 mg/kg, orally) of EyCD. The estrogenic and progestogenic effects of EyCD were further observed by administering it to immature Wistar rats by investigations of vaginal cornification, hormonal level, uterus weight, biochemical parameters, histopathology of the uterus and deciduoma formation, respectively.
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