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The and isomers of conjugated linoleic acid (CLA) are associated with anticancer and lipolytic effects in tissues, respectively, but in lactating cows, the latter isomer reduces the milk fat concentration, a detrimental aspect for the dairy industry, as it reduces the yield of milk derivatives. Therefore, the objective of this study was to evaluate the effect of providing protected palmitic acid (PA) to grazing lactating Holstein cows supplemented with soybean oil as a source of conjugated linoleic acid, on milk production, fat concentration and mitigation of milk fat depression. Nine multiparous Holstein cows were used, distributed in three groups of three cows each, with initial means of days in milk, live weight, milk production, and number of calvings: 124 ± 16 days, 494 ± 53 kg, 20.

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Protein glycation compromises the bioavailability of milk protein-derived lysine in vivo in healthy adult males: a double-blind randomized cross-over trial.

Am J Clin Nutr

January 2025

Department of Human Biology, NUTRIM Institute of Nutrition and Translational Research in Metabolism, Maastricht University Medical Centre+, Maastricht, the Netherlands. Electronic address:

Background: Industrial processing and storage of milk products can strongly increase protein glycation level. Previously, we have reported that ingestion of highly glycated milk protein attenuates the post-prandial rise in plasma lysine concentrations when compared to the ingestion of an equivalent amount of milk protein with a low glycation level. Whether the attenuated increase in plasma lysine availability is attributed to compromised protein digestion and subsequent lysine absorption remains to be established.

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New plant-based kefir fermented beverages as potential source of GABA.

J Food Sci Technol

February 2025

Food Science and Nutrition Department, School of Food Engineering, University of Campinas (UNICAMP), 80, Monteiro Lobato, Campinas, SP 13083-862 Brazil.

The aim of this study was to assess the gamma-aminobutyric acid (GABA) production in plant-based fermented beverages with kefir cultures (milk and water kefir). Water-soluble extracts of peanut and Brazil nut were evaluated as non-dairy substrates for the development of new bioactive beverages. A total of 12 formulations were developed and evaluated for their chemical composition, physical chemical characterization, and microbiological counts (aerobic mesophilic bacteria, lactobacilli, lactococci and yeasts).

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Infant respiratory infections modulate lymphocyte homing to breast milk.

Front Immunol

January 2025

Laboratorio de Pediatria Clinica (LIM36), Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, Brazil.

Introduction: Chemokines and their receptors are essential for leukocyte migration to several tissues, including human milk. Here, we evaluated the homing of T and B lymphocyte subsets to breast milk in response to ongoing respiratory infections in the nursing infant.

Methods: Blood and mature milk were collected from healthy mothers of nurslings with respiratory infections (Group I) and from healthy mothers of healthy nurslings (Group C).

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In recent years, global trends indicate consumer interest in functional foods. Thus, there is a trend to replace the use of artificial colors with natural colors that, in addition to being attractive to consumers, provide benefits to the biological functions of the human organism. The objective of this research was the solvent extraction of a natural dye from the roselle flower, its identification and evaluation of its behavior at different pH and temperatures.

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