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Heat Stroke-Induced Takotsubo Cardiomyopathy With a Concomitant Transient Brugada-Like Electrocardiogram.
Cureus
July 2023
Cardiovascular Surgery, Nagoya City University East Medical Center, Nagoya, JPN.
A 79-year-old man presented with impaired consciousness, fever with a body temperature of 41.1°C, and an electrocardiogram showing significant ST segment elevation in leads V1-6, coved-type ST elevation in leads V1-3, and partial right bundle branch block. Echocardiography revealed notable left ventricle dysfunction with apex-based akinesis.
View Article and Find Full Text PDFMeasuring Cardiac Output in a Swine Model.
J Vis Exp
May 2021
R Adams Cowley Shock Trauma Center, University of Maryland Medical System.
Swine are frequently used in medical research given their similar cardiac physiology to that of humans. Measuring cardiac parameters such as stroke volume and cardiac output are essential in this type of research. Contrast ventriculography, thermodilution, and pressure-volume loop (PV-loop) catheters can be used to accurately obtain cardiac performance data depending on which resources and expertise are available.
View Article and Find Full Text PDFRapid Surface Cooling by ThermoSuit System Dramatically Reduces Scar Size, Prevents Post-Infarction Adverse Left Ventricular Remodeling, and Improves Cardiac Function in Rats.
J Am Heart Assoc
June 2015
HMRI Cardiovascular Research Institute, Huntington Medical Research Institutes, Pasadena, CA (W.D., S.L.H., R.A.K.) Heart Institute of Good Samaritan Hospital, Los Angeles, CA (W.D., M.J.H., S.L.H., R.A.K.) Division of Cardiovascular Medicine of the Keck School of Medicine, University of Southern California, Los Angeles, CA (W.D., R.A.K.).
Background: The long-term effects of transient hypothermia by the non-invasive ThermoSuit apparatus on myocardial infarct (MI) scar size, left ventricular (LV) remodeling, and LV function were assessed in rat MI model.
Methods And Results: Rats were randomized to normothermic or hypothermic groups (n=14 in each group) and subjected to 30 minutes coronary artery occlusion and 6 weeks of reperfusion. For hypothermia therapy, rats were placed into the ThermoSuit apparatus at 2 minutes after the onset of coronary artery occlusion, were taken out of the apparatus when the core body temperature reached 32°C (in ≈8 minutes), and were then allowed to rewarm.
Central fever in patients with spontaneous intracerebral hemorrhage: predicting factors and impact on outcome.
BMC Neurol
February 2015
Departments of Neurology, the Agnes Ginges Center of Neurogenetics, Hebrew University-Hadassah Medical Center, P.O. Box 12000, Jerusalem, 91120, Israel.
Background: Central fever (CF) is defined as elevated temperature with no identifiable cause. We aimed to identify risk factors for developing CF among patients with spontaneous intracerebral hemorrhage (ICH) and to evaluate the impact of CF on outcome.
Methods: Patients included in our prospective stroke registry between 1/1/09 and 1/10/10 were studied.
Adipose-derived stem cell sheet transplantation therapy in a porcine model of chronic heart failure.
Transl Res
May 2015
Department of Cardiovascular Surgery, National Cardiovascular Center, Osaka, Japan.
Adipose-derived stem cells (ASCs) are a promising resource for cell transplantation therapy for damaged heart tissue. Cell death in the graft early after transplantation represents the main cause of unsatisfactory therapeutic efficacy, but tissue-engineered cell sheets grown in temperature-responsive cell culture dishes may enable improved engraftment of transplanted cells. We investigated the therapeutic potential of this method in chronic myocardial ischemia in swine.
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