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Secondary cryofibrinogenemia is related to more severe microangiopathic involvement in systemic sclerosis: results from a retrospective observational study.
Clin Rheumatol
January 2025
Rheumatology Unit, Scleroderma Unit, University Hospital of Modena, Via del Pozzo, 71-41125, Modena, Italy.
The aims of this study were to investigate the prevalence of cryofibrinogenemia in a cohort of patients with systemic sclerosis (SSc) regardless of clinical manifestations, who were admitted to our hospital and determine the associations among CF positivity, disease features and ongoing therapies. This was a monocentric and retrospective study. The inclusion criteria were a diagnosis of SSc (according to the ACR/EULAR 2013 classification criteria), regular administration of i.
View Article and Find Full Text PDFHenoch-Schönlein purpura with epididymo-orchitis: A rare extra-cutaneous manifestation.
Urol Case Rep
January 2025
Department of Pediatrics, Al-Ahli Hospital, Hebron, Palestine.
Henoch-Schönlein Purpura (HSP), or IgA vasculitis, is a systemic inflammatory disorder primarily affecting children. While common symptoms include purpura, abdominal pain, and arthritis, testicular involvement is rare. We report a case of a young boy presenting with severe scrotal pain and swelling, later identified as epididymo-orchitis secondary to HSP.
View Article and Find Full Text PDFToscana virus: a comprehensive review of 1,381 cases showing an emerging threat in the Mediterranean regions.
J Infect
January 2025
Unité des Virus Émergents (UVE: Aix-Marseille Univ, Università di Corsica, IRD 190, Inserm 1207, IRBA), France; Laboratoire des Infections Virales Aigues et Tropicales, Pole des Maladies Infectieuses, AP-HM Hopitaux Universitaires de Marseille, France; Le Service de Prévention du Risque Infectieux (LESPRI), CLIN AP-HM Hôpitaux Universitaires de Marseille, France.
Background: Toscana virus (TOSV) is a sand fly-borne phlebovirus causing central nervous system (CNS) infection in Mediterranean countries, during summer season. However, clinical aspects of the disease caused by this virus are poorly known by clinicians, so that its prevalence is probably underestimated due to a lack of diagnosis.
Study Design: The data was gathered from all available case series and retrospective studies identifying TOSV as the causative viral agent.
Self-limited cutaneous Langerhans Cell Histiocytosis: A case report.
Rev Esp Patol
January 2025
Anatomical Pathology Department, Hospital General Universitario de Castellón, Castellón, Spain.
Blueberry muffin baby syndrome is a condition initially described in 1960 to classify the cutaneous manifestations of newborns with rubella. Subsequently, congenital diseases related to TORCH syndrome and blood dyscrasias have been included under this syndrome. Among the conditions associated with this syndrome is Langerhans Cell Histiocytosis, an uncommon condition with variable involvement of one or more organs, often affecting the skin.
View Article and Find Full Text PDFCharacterization of Clinicopathological Features and Autoantibody Profiles in Patients with Cutaneous Lupus Erythematous: A Single-Center Retrospective Study.
Am J Clin Dermatol
January 2025
Department of Dermatology, University of Michigan, Ann Arbor, MI, USA.
Background: Cutaneous lupus erythematosus (CLE) is an autoimmune condition characterized by a wide range of clinical manifestations and limited treatment options. There is little research on the impact of commonly used diagnostic tests including antinuclear antibodies (ANA) and extractable nuclear antigens (ENA) on disease course or responsiveness to treatment.
Objective: This single-center retrospective cohort study aims to address this gap by characterizing clinicopathological characteristics, patient demographics, and treatment response among patients with CLE.
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