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Assessment of Reperfusion Efficacy of Altelyse Versus Actilyse in Patients with Acute Myocardial Infarction: A Phase 3, Randomized, Double-Blinded, Non-inferiority Clinical Trial.
Clin Drug Investig
January 2025
Department of Cardiology, Taleghani Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Background: Primary percutaneous coronary intervention (PPCI) and fibrinolytic or thrombolytic therapy are common treatments for ST-elevation myocardial infarction (STEMI). Primary percutaneous coronary intervention is more effective than thrombolytic therapy, but fibrinolytic therapy is still a preferable option for patients with limited access to healthcare. Alteplase is a tissue plasminogen activator (tPA) used to treat acute myocardial infarction, acute ischemic stroke, and pulmonary embolism.
View Article and Find Full Text PDFUsing Social Media to Promote Life Skills Among Adolescents: A Debate on Opportunities, Challenges, and Implications for Health and Education.
J Prev (2022)
January 2025
Department of Health and Prevention, Institute of Psychology, University of Greifswald, Robert-Blum-Str. 13, 17489, Greifswald, Germany.
The digitalization of society increasingly blurs boundaries between analog and digital worlds, offering opportunities such as telemedicine and global connectivity through digital platforms. However, it also presents risks, including cyberbullying, addiction potential, harmful content, misinformation, and privacy concerns from data breaches and surveillance technologies. Social media, with its global reach, amplifies both opportunities for positive engagement and the responsibility to navigate largely unregulated content.
View Article and Find Full Text PDFSpatial and temporal variability of soil moisture active and passive (SMAP) droughts and their impacts on vegetation in the Central Highlands of Vietnam.
Environ Monit Assess
January 2025
Faculty of Resources Management, Thai Nguyen University of Agriculture and Forestry, Mo Bach Str, Thai Nguyen City, Thai Nguyen Province, 250000, Vietnam.
Drought is a reoccurring natural phenomenon that presents significant challenges to agricultural production, ecosystem stability, and water resource management. The Central Highlands of Vietnam, a major region of industrial crops and vegetation ecosystems, has become increasingly vulnerable to drought impacts. Despite this vulnerability, limited research has explored the specific characteristics of drought and its seasonal effects on vegetation ecosystems in the region.
View Article and Find Full Text PDFUnveiling pterion variability: a meta-analytic approach to enhance neurosurgical precision.
Surg Radiol Anat
January 2025
Department of Clinical-Surgical, Diagnostic and Pediatric Sciences, University of Pavia, Pavia, Italy.
Purpose: This meta-analytical systematic review aims at investigating the variability of the pterion, focusing on its morphological types and precise distances from various bony landmarks. Additionally, the neurosurgical significance of this critical cranial landmark is examined in depth.
Methods: The systematic review was conducted following PRISMA 2020 and Evidence-based Anatomy Workgroup guidelines for anatomical studies.
Effectiveness of a multicentre randomized controlled trial with three different nurse-led intervention management programmes for patients with heart failure: the main results of the MEETinCY study.
Eur J Cardiovasc Nurs
January 2025
NHSBT Clinical Trials Unit, Unit, NHSBT CTU, Long Road, Cambridge CB2 0PT, UK.
Aims: A single-blinded, multicentred randomized controlled trial (RCT) was employed to examine the effectiveness of a 3-month telephone follow-up, a telephone follow-up with education before discharge, or education only before discharge on the heart failure (HF) knowledge, HF self-care management, and health-related quality of life (HR-QoL) in patients with HF by a nurse specialist.
Methods And Results: This is a multicentre RCT with three different intervention groups (IGs) and one control group. Participants in the first IG received education on HF self-management principles before discharge.
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