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A lack of sexual autonomy is associated with increased loneliness in young mothers.

BMC Womens Health

January 2025

Department of Neuroscience, Physiology and Pharmacology, University College London, 21 University Street, London, WC1E 6DE, UK.

Background: Loneliness is a significant risk factor for both mental and physical health issues, including depression and increased mortality. Loneliness is reported at higher levels during life transitions, such as the transition to motherhood. Loneliness in mothers has far-reaching detrimental impacts on both mother and child, such as an increased risk of maternal depression and child abuse.

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Objectives: To investigate potential sleep inequities between the infants of Māori and non-Māori mothers in Aotearoa New Zealand, identify socio-ecological factors associated with infant sleep, and determine features of infant sleep that contribute to a mother-perceived infant sleep problem.

Design: Secondary analysis of longitudinal data from the Moe Kura: Mother and Child, Sleep and Well-being in Aotearoa New Zealand study when infants were approximately 12 weeks old.

Participants: 383 Māori and 702 non-Māori mother-infant dyads.

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Three-year-old development: The relationship of child health and parenting stress to neurocognition.

J Pediatr Nurs

January 2025

Department of Health Promotion and Disease Prevention, College of Nursing, University of Tennessee Health Science Center, 847 Union Ave, Memphis, TN 38163, USA.

Purpose: This study examined parenting stress and child special healthcare needs to child neurocognitive development (NCD).

Design And Methods: This secondary analysis used data from the primary study, a longitudinal cohort study of mother-child dyads. Multivariable regression models examined the associations between parenting stress and child special healthcare needs with NCD.

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Tire wear particles (TWP) are one of the main sources of microplastic (MP) pollution in the marine environment, causing adverse effects on marine life and attracting increasing attention. This study aimed to investigate the chemical composition of TWP (particles and leachate) and their toxic effects on Brachionus plicatilis. The results showed that Zn and acenaphthene were the most frequently detected compounds in the three TWP treatments.

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LncRNA-MEG3/miR-93-5p/SMAD7 axis mediates proliferative and inflammatory phenotypes of fibroblast-like synoviocytes in rheumatoid arthritis.

Int J Biol Macromol

January 2025

Department of Pharmacy, The First Affiliated Hospital of Anhui Medical University, Hefei 230022, China; The Grade 3 Pharmaceutical Chemistry Laboratory of State Administration of Traditional Chinese Medicine, Hefei 230022, China. Electronic address:

Synovial hyperplasia, inflammation and immune cell infiltration are the central pathological basis of rheumatoid arthritis (RA). Nonetheless, the cellular, molecular and immunological mechanisms of RA remain poorly understood. An integrated analysis of single-cell RNA (scRNA) and bulk RNA sequencing datasets‌ aimed to unravel the cellular landscape, differentiation trajectory, transcriptome signature, and immunoinfiltration feature of RA synovium.

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