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Coexistence of the blaZ gene and selected virulence determinants in multidrug-resistant Staphylococcus aureus: insights from three Nigerian tertiary hospitals.
BMC Infect Dis
November 2024
Department of Pharmaceutical Microbiology, University of Ibadan, Ibadan, Oyo State, Nigeria.
Background And Purpose: Infections caused by β-lactamase-producing strains of Staphylococcus aureus have become increasingly difficult to treat due to the expression of multiple virulence factors. This has heightened concerns about managing S. aureus-related infections.
View Article and Find Full Text PDFTrends in the Prevalence of Antimicrobial Resistance in Escherichia coli Isolated from Outpatient Urine Cultures in French Amazonia.
Am J Trop Med Hyg
August 2024
Tropical and Infectious Diseases Department, Cayenne General Hospital, French Guiana.
Article Synopsis
- * Out of 3,443 E. coli isolates, a significant percentage (64.4%) were β-lactamase producers, with common resistance mechanisms being penicillinase production; 6.1% had extended-spectrum β-lactamase (ESBL).
- * While susceptibility to certain antibiotics like amoxicillin/clavulanic acid declined, ciprofloxacin showed increased susceptibility; overall, resistance trends necessitate ongoing monitoring and efforts to reduce antibiotic use in the community.
Antibacterial Activity of Surfactin and Synergistic Effect with Conventional Antibiotics Against Methicillin-Resistant Isolated from Patients with Diabetic Foot Ulcers.
Diabetes Metab Syndr Obes
November 2023
Department of Laboratory Medicine, the Affiliated Hospital of Southwest Medical University, Luzhou, People's Republic of China.
Introduction: The prevalence of diabetic foot ulcers (DFUs) is increasing, leading to a huge financial burden and human suffering. Furthermore, antibiotic resistance is an urgent problem in the realm of clinical practice. Antimicrobial peptides are an effective and feasible strategy for combating infections caused by drug-resistant bacteria.
View Article and Find Full Text PDFStaphylococcal Resistance Patterns, and SCC Cassette Genes in the Nasopharyngeal Microbiota of Pregnant Women.
Int J Mol Sci
April 2023
Department of Pharmaceutical Microbiology, Medical University of Lublin, W. Chodźki Str. 1, 20-093 Lublin, Poland.
Antimicrobial resistance in spp. colonising the nasopharynx can create risk factors of therapeutic treatment failure or prophylaxis in pregnant women. Resistance is mostly encoded on plasmids (e.
View Article and Find Full Text PDFSeven Years of Culture Collection of : Antimicrobial Resistance and Molecular Epidemiology.
Microb Drug Resist
March 2023
Department Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy.
The emergence of isolates displaying resistance to antimicrobials, in particular to ceftriaxone monotherapy or ceftriaxone plus azithromycin, represents a global public health concern. This study aimed to analyze the trend of antimicrobial resistance in a 7-year isolate collection retrospective analysis in Italy. Molecular typing on a subsample of gonococci was also included.
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